(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
- CAS
- 1803026-54-1
- Formula
- C16H12F6N4O
- MW
- 390.28 g/mol
ZX-022781
Impurity reference standards
Sitagliptin impurity standards
Zemixal lists 94 reference materials related to Sitagliptin, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 6 pharmacopoeial impurities and 3 metabolites or hydroxylated analogues.
94reference materials
6pharmacopoeial
3metabolites
Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. Typical uses are method development and validation, relative response factor work, forced degradation studies and the impurity sections of ANDA, DMF or CEP filings.
By impurity type
Pharmacopoeial6EP, USP, BP or JP named impurities
Metabolites3Hydroxy, desmethyl and conjugated forms
Counts are based on product names. One compound can fall into more than one type.
All Sitagliptin reference materials
1–60 of 94 standards
(R)-3-((tert-Butoxycarbonyl)amino)-4-(2-fluorophenyl)butanoic Acid
- CAS
- 218608-98-1
- Formula
- C15H20FNO4
- MW
- 297.32 g/mol
ZX-042975
(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-difluorophenyl)butanoic Acid
- CAS
- 851307-12-5
- Formula
- C15H19F2NO4
- MW
- 315.31 g/mol
ZX-022782
(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid
- CAS
- 486459-98-7
- Formula
- C15H19F2NO4
- MW
- 315.31 g/mol
ZX-032505
(R)-3-((tert-Butoxycarbonyl)amino)-4-(4-fluorophenyl)butanoic Acid
- CAS
- 218609-00-8
- Formula
- C15H20FNO4
- MW
- 297.32 g/mol
ZX-042976
(R)-Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate
- CAS
- 1234321-83-5
- Formula
- C13H14F3NO3
- MW
- 289.25 g/mol
ZX-022783
(R)-Sitagliptin Methyl-Ester Hydrochloride
- CAS
- 1374985-05-3
- Formula
- C11H13ClF3NO2
- MW
- 283.67 g/mol
ZX-026959
(R)-tert-Butyl (4-(1H-imidazol-1-yl)-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate
- CAS
- 1364122-90-6
- Formula
- C18H20F3N3O3
- MW
- 383.4 g/mol
ZX-026962
(R)-tert-butyl (4-morpholino-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate
- Formula
- C19H25F3N2O4
- MW
- 402.41 g/mol
ZX-011849
1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine
- CAS
- 762240-99-3
- Formula
- C4H4ClF3N2O2
- MW
- 204.53 g/mol
ZX-032502
2-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)acetohydrazide
- CAS
- 1485732-85-1
- Formula
- C8H11F3N6O
- MW
- 264.21 g/mol
ZX-026964
2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium
- CAS
- 7685-16-7
- Formula
- C19H15IN5O2+
- MW
- 472.3 g/mol
ZX-011970
3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride
- CAS
- 1909337-07-0
- Formula
- C10H11ClF3NO2
- MW
- 269.65 g/mol
ZX-032846
3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid
- CAS
- 1620129-74-9
- Formula
- C15H18F3NO4
- MW
- 333.3 g/mol
ZX-022785
5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole
- CAS
- 723286-98-4
- Formula
- C4H2ClF3N2O
- MW
- 186.52 g/mol
ZX-026958
Ethyl-3-oxo-4-(2,4,5-trifluorophenyl)butanoate
- CAS
- 1151240-88-8
- Formula
- C12H11F3O3
- MW
- 260.21 g/mol
ZX-042506
Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride
- CAS
- 1909309-14-3
- Formula
- C11H13ClF3NO2
- MW
- 283.67 g/mol
ZX-036187
N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide
- CAS
- 849832-73-1
- Formula
- C6H9F3N4O
- MW
- 210.16 g/mol
ZX-032503
Questions
Sitagliptin impurities, answered
How many Sitagliptin impurity standards does Zemixal list?
The catalogue currently lists 94 compounds for Sitagliptin, including 6 pharmacopoeial impurities and 3 metabolites or hydroxylated analogues. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Sitagliptin impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Sitagliptin impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.