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API Impurities

42-O-tert-Butyldimethylsilyloxyethyl Rapamycin

Reference StandardAvailable on request

Order 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin (CAS 159351-68-5) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes
42-O-tert-Butyldimethylsilyloxyethyl Rapamycin chemical structure
CAS number159351-68-5
FormulaC59H97NO14Si
Molar mass1072.5 g/mol
Physical formSolid
HS code38229090
InChIKeyOCAIMYVVCQFDKI-JFPHMNFRSA-N

About 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin

42-O-tert-Butyldimethylsilyloxyethyl Rapamycin is supplied by Zemixal as a characterised reference material for Everolimus analysis. For your records (Reference Standard), the material is defined by CAS 159351-68-5, formula C59H97NO14Si and molar mass 1072.5 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

It carries the GHS signal word Danger (H301, H311, H331 and H360), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Everolimus

See every impurity, metabolite and related compound we list for this API.

Everolimus standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin
Product name42-O-tert-Butyldimethylsilyloxyethyl Rapamycin
Catalogue numberZX-029411
CAS number159351-68-5
IUPAC name(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-12-[(2R)-1-[(1S,3R,4R)-4-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]-3-methoxycyclohexyl]propan-2-yl]-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular formulaC59H97NO14Si
Molar mass1072.5 g/mol
Exact mass1071.6678
GradeReference Standard
Physical formSolid
H-bond donors / acceptors2 / 14
Topological polar surface area194 Ų
HS code38229090
InChIKeyOCAIMYVVCQFDKI-JFPHMNFRSA-N
SMILESC[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO[Si](C)(C)C(C)(C)C)C)/C)O)OC)C)C)/C)OC
PubChem CID71608050
Synonyms40-O-(2-(t-butyldimethylsilyl)oxy)ethyl-rapamycin, 40-O-[2-(t-butyldimethylsilyl)oxy]ethyl-rapamycin, Rapamycin 42-[2-(tert-butyldimethylsilyloxy)ethyl] ether, Rapamycin, 42-O-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-, 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv.

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS08 Health hazard
Health hazard

Signal word Danger

  • H301Toxic if swallowed
  • H311Toxic in contact with skin
  • H331Toxic if inhaled
  • H360May damage fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P318, P319, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin

Which CAS number identifies 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin?
42-O-tert-Butyldimethylsilyloxyethyl Rapamycin is registered under CAS 159351-68-5. You may also see it listed as 40-O-(2-(t-butyldimethylsilyl)oxy)ethyl-rapamycin, 40-O-[2-(t-butyldimethylsilyl)oxy]ethyl-rapamycin, Rapamycin 42-[2-(tert-butyldimethylsilyloxy)ethyl] ether. Our catalogue number for this item is ZX-029411.
What are the formula and molar mass of 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin?
For 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin, its formula is C59H97NO14Si and its molar mass is 1072.5 g/mol. InChIKey OCAIMYVVCQFDKI-JFPHMNFRSA-N lets you match it in any structure database.
How is 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin used in pharmaceutical QC?
42-O-tert-Butyldimethylsilyloxyethyl Rapamycin is a characterised reference material linked to Everolimus. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin to my country?
Yes. Because 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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