Impurity reference standards

Everolimus impurity standards

This page brings together 11 Everolimus related compounds that analytical teams use to identify, quantify and control impurities in the active ingredient and the finished dosage form. The range includes 3 pharmacopoeial impurities, 1 isotope-labelled standard and 1 metabolite or hydroxylated analogue.

11reference materials

3pharmacopoeial

1isotope labelled

1metabolites

Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. Laboratories use them to validate related-substance methods, set specification limits under ICH Q3A and Q3B, and identify unknown peaks in stability samples.

By impurity type

Pharmacopoeial3EP, USP, BP or JP named impurities

Isotope labelled1Deuterated, 13C or 15N internal standards

Metabolites1Hydroxy, desmethyl and conjugated forms

Counts are based on product names. One compound can fall into more than one type.

All Everolimus reference materials

1–11 of 11 standards

2,6-Di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one

CAS: 2607-52-5
Formula: C₁₅H₂₂O
MW: 218.33 g/mol

ZX-011955

42-O-tert-Butyldimethylsilyloxyethyl Rapamycin

CAS: 159351-68-5
Formula: C₅₉H₉₇NO₁₄Si
MW: 1072.5 g/mol

ZX-029411

Everolimus EP Impurity B

CAS: 1062122-63-7
Formula: C₅₃H₈₃NO₁₄
MW: 958.2 g/mol

ZX-029412

Everolimus EP Impurity D

CAS: 2760174-96-5
Formula: C₅₃H₈₃NO₁₄
MW: 958.2 g/mol

ZX-029414

Everolimus EP Impurity E

CAS: 1237826-25-3
Formula: C₅₂H₇₉NO₁₄
MW: 942.2 g/mol

ZX-029409

Everolimus IP Impurity E

CAS: 147438-30-0
Formula: C₃₂H₄₉NO₉
MW: 591.7 g/mol

ZX-024644

Everolimus Isomer C

CAS: 908340-97-6
Formula: C₅₃H₈₃NO₁₄
MW: 958.2 g/mol

ZX-029413

Everolimus Ring Opening Impurity

CAS: 1708118-13-1
Formula: C₅₃H₈₃NO₁₄
MW: 958.2 g/mol

ZX-029408

Everolimus-d4

CAS: 1338452-54-2
Formula: C₅₃H₈₃NO₁₄
MW: 962.2 g/mol

ZX-033448

O-Desmethyl Everolimus

CAS: 745779-75-3
Formula: C₅₂H₈₁NO₁₄
MW: 944.2 g/mol

ZX-029407

Seco Everolimus B

CAS: 769905-89-7
Formula: C₅₃H₈₅NO₁₅
MW: 976.2 g/mol

ZX-029410

Questions

Everolimus impurities, answered

What Everolimus reference materials are available?

The catalogue currently lists 11 compounds for Everolimus, including 3 pharmacopoeial impurities, 1 isotope-labelled standard and 1 metabolite or hydroxylated analogue. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.

What documents come with a Everolimus impurity standard?

A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.

Can Zemixal make a Everolimus impurity that is not listed?

Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.

Are isotope-labelled Everolimus standards available?

Yes. 1 stable-isotope labelled compound is listed, suitable as internal standards for LC-MS bioanalysis and trace impurity quantitation.