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Antidiabetic, Hormone & Metabolic APIs

Betamethasone

IP/BP/USPAvailable on request

Betamethasone (CAS 378-44-9) supplier Zemixal: C22H29FO5, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-004118.

Pack sizes
Betamethasone chemical structure
CAS number378-44-9
FormulaC22H29FO5
Molar mass392.5 g/mol
Physical formPowder
InChIKeyUREBDLICKHMUKA-DVTGEIKXSA-N
IUPAC name(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

About Betamethasone

Betamethasone is part of the Zemixal antidiabetic, Hormone & Metabolic APIs range. Identity at a glance (IP/BP/USP): CAS 378-44-9, formula C22H29FO5 and molar mass 392.5 g/mol. It is handled as a powder.

Where it is used

  • Pharmaceutical formulation
  • Generic drug development

Safe handling

It carries the GHS signal word Danger (H330, H360, H372 and H373), so wear gloves and eye protection and work with good ventilation.

Order it in 1 kg, 5 kg and 25 kg packs or ask for a bulk quotation. Every shipment includes a batch certificate of analysis and a 16-section SDS. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Betamethasone

See every impurity, metabolite and related compound we list for this API.

Betamethasone standards

Typical uses

  • Pharmaceutical formulation
  • Generic drug development

Applications

Grade guides

Specifications and identifiers

Specifications of Betamethasone
Product nameBetamethasone
Catalogue numberZX-004118
CAS number378-44-9
IUPAC name(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formulaC22H29FO5
Molar mass392.5 g/mol
Exact mass392.1999
GradeIP/BP/USP
Physical formPowder
XLogP31.9
H-bond donors / acceptors3 / 6
Topological polar surface area94.8 Ų
InChIKeyUREBDLICKHMUKA-DVTGEIKXSA-N
SMILESC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
PubChem CID9782
SynonymsBetadexamethasone, Flubenisolone, Celestene, beta-Methasone, Desacort-Beta, Betametasone, beta-Methasone alcohol, SCH 4831, 9-Fluoro-16beta-methylprednisolone, 9alpha-Fluoro-16beta-methylprednisolone, SCH-4831, 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Danger

  • H330Fatal if inhaled
  • H360May damage fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure
  • H373May causes damage to organs through prolonged or repeated exposure
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements P203, P260, P264, P270, P271, P273, P280, P284, P304 + P340, P316, P318, P319, P320, P391, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Betamethasone
1 kgQuoted on request
5 kgQuoted on request
25 kgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Betamethasone

Which CAS number identifies Betamethasone?
Betamethasone is registered under CAS 378-44-9. You may also see it listed as Betadexamethasone, Flubenisolone, Celestene. Our catalogue number for this item is ZX-004118.
What are the formula and molar mass of Betamethasone?
For Betamethasone, its formula is C22H29FO5 and its molar mass is 392.5 g/mol. The systematic (IUPAC) name is (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one. InChIKey UREBDLICKHMUKA-DVTGEIKXSA-N lets you match it in any structure database.
How is Betamethasone used in pharmaceutical QC?
Betamethasone is a characterised reference material linked to Betamethasone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Betamethasone?
This listing is IP/BP/USP grade. Standard packs are 1 kg, 5 kg, 25 kg. Larger quantities and custom packing can be quoted on request.
Which documents come with Betamethasone?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Betamethasone to my country?
Yes. Because Betamethasone is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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