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Pharmacopeial Impurities (EP / USP / BP)

Clobetasol Propionate EP Impurity B

Reference StandardAvailable on request

Order Clobetasol Propionate EP Impurity B (CAS 1356190-17-4) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes
Clobetasol Propionate EP Impurity B chemical structure
CAS number1356190-17-4
FormulaC22H26ClFO3
Molar mass392.9 g/mol
Physical formSolid
HS code38229090
InChIKeyYWRGNRUKHBYFTD-QEYSUVLUSA-N
IUPAC name(8S,9R,10S,11S,13S,14S)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one

About Clobetasol Propionate EP Impurity B

Analytical teams working on Clobetasol use Clobetasol Propionate EP Impurity B as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 1356190-17-4, formula C22H26ClFO3 and molar mass 392.9 g/mol. It is handled as a solid.

Typical applications

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Safe handling

Classified under GHS with signal word Danger and hazard statements H360, H373 and H413. Read the SDS before first use.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Clobetasol

See every impurity, metabolite and related compound we list for this API.

Clobetasol standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Clobetasol Propionate EP Impurity B
Product nameClobetasol Propionate EP Impurity B
Catalogue numberZX-021253
CAS number1356190-17-4
IUPAC name(8S,9R,10S,11S,13S,14S)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular formulaC22H26ClFO3
Molar mass392.9 g/mol
Exact mass392.1555
GradeReference Standard
Physical formSolid
XLogP33.1
H-bond donors / acceptors1 / 4
Topological polar surface area54.4 Ų
HS code38229090
InChIKeyYWRGNRUKHBYFTD-QEYSUVLUSA-N
SMILESCC1=C([C@]2(C[C@@H]([C@]3([C@H]([C@@H]2C1)CCC4=CC(=O)C=C[C@@]43C)F)O)C)C(=O)CCl
PubChem CID13067007
SynonymsClobetasol Propionate - Impurity B, (11beta)-21-Chloro-9-fluoro-11-hydroxy-16-methylpregna-1,4,16-triene-3,20-dione, 21-Chloro-9-fluoro-11beta-hydroxy-16-methylpregna-1,4,16-triene-3,20-dione, Pregna-1,4,16-triene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-, (11beta)-, Clobetasol Propionate Impurity B, (11, A)-21-Chloro-9-fluoro-11-hydroxy-16-methylpregna-1,4,16-triene-3,20-dione

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H360May damage fertility or the unborn child
  • H373May causes damage to organs through prolonged or repeated exposure
  • H413May cause long lasting harmful effects to aquatic life

Precautionary statements P203, P260, P273, P280, P318, P319, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Clobetasol Propionate EP Impurity B
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Clobetasol Propionate EP Impurity B

Which CAS number identifies Clobetasol Propionate EP Impurity B?
Clobetasol Propionate EP Impurity B is registered under CAS 1356190-17-4. You may also see it listed as Clobetasol Propionate - Impurity B, (11beta)-21-Chloro-9-fluoro-11-hydroxy-16-methylpregna-1,4,16-triene-3,20-dione, 21-Chloro-9-fluoro-11beta-hydroxy-16-methylpregna-1,4,16-triene-3,20-dione. Our catalogue number for this item is ZX-021253.
What are the formula and molar mass of Clobetasol Propionate EP Impurity B?
For Clobetasol Propionate EP Impurity B, its formula is C22H26ClFO3 and its molar mass is 392.9 g/mol. The systematic (IUPAC) name is (8S,9R,10S,11S,13S,14S)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one. InChIKey YWRGNRUKHBYFTD-QEYSUVLUSA-N lets you match it in any structure database.
How is Clobetasol Propionate EP Impurity B used in pharmaceutical QC?
Clobetasol Propionate EP Impurity B is a characterised reference material linked to Clobetasol. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Clobetasol Propionate EP Impurity B?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Clobetasol Propionate EP Impurity B?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Clobetasol Propionate EP Impurity B to my country?
Yes. Because Clobetasol Propionate EP Impurity B is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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