(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
- CAS
- 2223677-64-1
- Formula
- C22H20ClFN4O3
- MW
- 442.9 g/mol
ZX-020501
API Impurities
Diethyl
Reference StandardAvailable on request
Order Diethyl (CAS 618061-76-0) online at Zemixal: C24H27ClFN4O6P, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-020502.
CAS number618061-76-0
FormulaC24H27ClFN4O6P
Molar mass552.9 g/mol
Physical formSolid
HS code38229090
InChIKeyFNGRCLBEXKFSST-INIZCTEOSA-N
IUPAC nameN-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-diethoxyphosphorylacetamide
About Diethyl
Zemixal lists Diethyl for laboratories that identify, quantify or control Afatinib and its related substances. Key data (Reference Standard): CAS 618061-76-0, formula C24H27ClFN4O6P and molar mass 552.9 g/mol. It is handled as a solid.
Where it is used
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.
Reference standards for Afatinib
See every impurity, metabolite and related compound we list for this API.
Afatinib standardsTypical uses
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Applications
Specifications and identifiers
| Product name | Diethyl |
|---|---|
| Catalogue number | ZX-020502 |
| CAS number | 618061-76-0 |
| IUPAC name | N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-diethoxyphosphorylacetamide |
| Molecular formula | C24H27ClFN4O6P |
| Molar mass | 552.9 g/mol |
| Exact mass | 552.1341 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 3.9 |
| H-bond donors / acceptors | 2 / 10 |
| Topological polar surface area | 121 Ų |
| HS code | 38229090 |
| InChIKey | FNGRCLBEXKFSST-INIZCTEOSA-N |
| SMILES | CCOP(=O)(CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4)OCC |
| PubChem CID | 15606393 |
| Synonyms | Diethyl (S)-2-Amino-2-oxoethyl Phosphonate Afatinib |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Diethyl
Which CAS number identifies Diethyl?
Diethyl is registered under CAS 618061-76-0. You may also see it listed as Diethyl (S)-2-Amino-2-oxoethyl Phosphonate Afatinib. Our catalogue number for this item is ZX-020502.
What are the formula and molar mass of Diethyl?
For Diethyl, its formula is C24H27ClFN4O6P and its molar mass is 552.9 g/mol. The systematic (IUPAC) name is N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-diethoxyphosphorylacetamide. InChIKey FNGRCLBEXKFSST-INIZCTEOSA-N lets you match it in any structure database.
How is Diethyl used in pharmaceutical QC?
Diethyl is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Diethyl?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Diethyl?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Diethyl to my country?
Yes. Diethyl ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.
More Afatinib standards
More in API Impurities
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide
- CAS
- 2121530-37-6
- Formula
- C22H20ClFN4O4
- MW
- 458.9 g/mol
ZX-020500
(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
- CAS
- 2413212-09-4
- Formula
- C18H17ClN4O2
- MW
- 356.8 g/mol
ZX-020499
(S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- CAS
- 2223677-63-0
- Formula
- C24H25Cl2N5O3
- MW
- 502.4 g/mol
ZX-020506
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