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API Reference Standards

Dolutegravir

Reference StandardAvailable on request

Dolutegravir (CAS 1051375-16-6) supplier Zemixal. Request a quote with price, lead time and documents. Part of our API Reference Standards range.

Pack sizes
Dolutegravir chemical structure
CAS number1051375-16-6
FormulaC20H19F2N3O5
Molar mass419.4 g/mol
Physical formSolid
HS code38229090
InChIKeyRHWKPHLQXYSBKR-BMIGLBTASA-N
IUPAC name(3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide

About Dolutegravir

Dolutegravir is supplied by Zemixal as a characterised reference material for Dolutegravir analysis. Identity at a glance (Reference Standard): CAS 1051375-16-6, formula C20H19F2N3O5 and molar mass 419.4 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Identification & assay
  • Method development & validation
  • QC reference material

Storage and safety notes

It carries the GHS signal word Warning (H400 and H410), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Dolutegravir

See every impurity, metabolite and related compound we list for this API.

Dolutegravir standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Dolutegravir
Product nameDolutegravir
Catalogue numberZX-021452
CAS number1051375-16-6
IUPAC name(3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide
Molecular formulaC20H19F2N3O5
Molar mass419.4 g/mol
Exact mass419.1293
GradeReference Standard
Physical formSolid
XLogP32.4
H-bond donors / acceptors2 / 8
Topological polar surface area99.2 Ų
HS code38229090
InChIKeyRHWKPHLQXYSBKR-BMIGLBTASA-N
SMILESC[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
PubChem CID54726191
SynonymsDolutegravir (GSK1349572), Dolutegravir DTG, Dolutegravir (USAN), 3s3m, 3s3n, 3s3o, EX-A1695

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H400Very toxic to aquatic life
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements P273, P391, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Dolutegravir
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Dolutegravir

Which CAS number identifies Dolutegravir?
Dolutegravir is registered under CAS 1051375-16-6. You may also see it listed as Dolutegravir (GSK1349572), Dolutegravir DTG, Dolutegravir (USAN). Our catalogue number for this item is ZX-021452.
What are the formula and molar mass of Dolutegravir?
For Dolutegravir, its formula is C20H19F2N3O5 and its molar mass is 419.4 g/mol. The systematic (IUPAC) name is (3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide. InChIKey RHWKPHLQXYSBKR-BMIGLBTASA-N lets you match it in any structure database.
How is Dolutegravir used in pharmaceutical QC?
Dolutegravir is a characterised reference material linked to Dolutegravir. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Dolutegravir?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Dolutegravir?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Dolutegravir to my country?
Yes. Because Dolutegravir is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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