(2R,3S)-3-Amino-2-hydroxy-3-phenylpropanoic acid hydrochloride
- CAS
- 132201-32-2
- Formula
- C9H12ClNO3
- MW
- 217.65 g/mol
ZX-044837
Impurity reference standards
Dolutegravir impurity standards
37 characterised compounds linked to Dolutegravir are catalogued here, from named pharmacopoeial impurities to synthesis intermediates and breakdown products. Highlights of the range are 4 metabolites or hydroxylated analogues and 1 degradation product.
37reference materials
4metabolites
1degradants
Batches are supplied with a certificate of analysis, and the supporting spectra can be sent ahead of a purchase order so your QA team can review them. Typical uses are method development and validation, relative response factor work, forced degradation studies and the impurity sections of ANDA, DMF or CEP filings.
By impurity type
Metabolites4Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products
Counts are based on product names. One compound can fall into more than one type.
All Dolutegravir reference materials
1–37 of 37 standards
(4R,12AR)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid
- CAS
- 2315439-81-5
- Formula
- C14H16N2O6
- MW
- 308.29 g/mol
ZX-029055
(4S,12AS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
- CAS
- 2730133-58-9
- Formula
- C14H16N2O6
- MW
- 308.29 g/mol
ZX-029056
(R)-2-(4-Hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
- CAS
- 2710626-41-6
- Formula
- C14H16N2O6
- MW
- 308.29 g/mol
ZX-029054
(Z)-Methyl2-[(Dimethylamino)methylene]-4-methoxy-3-oxobutanoate
- CAS
- 127958-23-0
- Formula
- C9H15NO4
- MW
- 201.22 g/mol
ZX-039054
1-(2,2-Dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylic Acid
- CAS
- 2651309-06-5
- Formula
- C12H15NO8
- MW
- 301.25 g/mol
ZX-029053
1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic Acid
- CAS
- 1335210-23-5
- Formula
- C13H17NO8
- MW
- 315.28 g/mol
ZX-024329
4-Oxo-3-[(Phenylmethyl)oxy]-4H-pyran-2-carboxylic acid
- CAS
- 119736-16-2
- Formula
- C13H10O5
- MW
- 246.21 g/mol
ZX-036678
N-[(2,4-Difluorophenyl)methylene]-2,4-difluoro-benzenemethanamine
- CAS
- 1916490-96-4
- Formula
- C14H9F4N
- MW
- 267.22 g/mol
ZX-029052
Questions
Dolutegravir impurities, answered
How many Dolutegravir impurity standards does Zemixal list?
The catalogue currently lists 37 compounds for Dolutegravir, including 4 metabolites or hydroxylated analogues and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Dolutegravir impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Dolutegravir impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.