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Pharmacopeial Impurities (EP / USP / BP)

Hydrocortisone EP Impurity K

Reference StandardAvailable on request

Hydrocortisone EP Impurity K (CAS 640-87-9) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery. Catalogue no. ZX-020289.

Pack sizes
Hydrocortisone EP Impurity K chemical structure
CAS number640-87-9
FormulaC23H32O5
Molar mass388.5 g/mol
Physical formSolid
HS code38229090
InChIKeyHPAKILCZTKWIFK-JZTHCNPZSA-N
IUPAC name[2-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

About Hydrocortisone EP Impurity K

Zemixal lists Hydrocortisone EP Impurity K for laboratories that identify, quantify or control Hydrocortisone and its related substances. Key data (Reference Standard): CAS 640-87-9, formula C23H32O5 and molar mass 388.5 g/mol. It is handled as a solid.

Where it is used

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Handling and storage

Classified under GHS with signal word Warning and hazard statements H361 and H411. Read the SDS before first use.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Hydrocortisone

See every impurity, metabolite and related compound we list for this API.

Hydrocortisone standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Hydrocortisone EP Impurity K
Product nameHydrocortisone EP Impurity K
Catalogue numberZX-020289
CAS number640-87-9
IUPAC name[2-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formulaC23H32O5
Molar mass388.5 g/mol
Exact mass388.225
GradeReference Standard
Physical formSolid
XLogP32.5
H-bond donors / acceptors1 / 5
Topological polar surface area80.7 Ų
HS code38229090
InChIKeyHPAKILCZTKWIFK-JZTHCNPZSA-N
SMILESCC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
PubChem CID101816
Synonyms17a-Hydroxy-11-deoxycorticosterone-21-acetate, 17α-Hydroxy-11-deoxycorticosterone-21-acetate, Cortexolone Impurity C, 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,20-dione, 11-Deoxycortisol 21-acetate, cortexolone 21-acetate, Pregn-4-ene-3,20-dione, 21-(acetyloxy)-17-hydroxy-, 17-alpha,21-Dihydroxypregn-4-ene-3,20-dione 21-acetate, 17-Hydroxy-3,20-dioxopregn-4-en-21-yl acetate, 17-Hydroxy-3,20-dioxopregn-4-en-21-yl Acetate (Reichstein's Substance S 21-Acetate), 11-Deoxy-17-hydrocorticosterone 21-acetate, Reichstein's S acetate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H361Suspected of damaging fertility or the unborn child
  • H411Toxic to aquatic life with long lasting effects

Precautionary statements P203, P273, P280, P318, P391, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Hydrocortisone EP Impurity K
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Hydrocortisone EP Impurity K

Which CAS number identifies Hydrocortisone EP Impurity K?
Hydrocortisone EP Impurity K is registered under CAS 640-87-9. You may also see it listed as 17a-Hydroxy-11-deoxycorticosterone-21-acetate, 17α-Hydroxy-11-deoxycorticosterone-21-acetate, Cortexolone Impurity C. Our catalogue number for this item is ZX-020289.
What are the formula and molar mass of Hydrocortisone EP Impurity K?
For Hydrocortisone EP Impurity K, its formula is C23H32O5 and its molar mass is 388.5 g/mol. The systematic (IUPAC) name is [2-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate. InChIKey HPAKILCZTKWIFK-JZTHCNPZSA-N lets you match it in any structure database.
How is Hydrocortisone EP Impurity K used in pharmaceutical QC?
Hydrocortisone EP Impurity K is a characterised reference material linked to Hydrocortisone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Hydrocortisone EP Impurity K?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Hydrocortisone EP Impurity K?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Hydrocortisone EP Impurity K to my country?
Yes. Because Hydrocortisone EP Impurity K is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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