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API Reference Standards

Larotrectinib WS

Reference StandardAvailable on request

Buy Larotrectinib WS (CAS 1223403-58-4) from Zemixal. Lab and bulk packs, batch COA, fast global delivery. Part of our API Reference Standards range.

Pack sizes
Larotrectinib WS chemical structure
CAS number1223403-58-4
FormulaC21H22F2N6O2
Molar mass428.4 g/mol
Physical formSolid
HS code38229090
InChIKeyNYNZQNWKBKUAII-KBXCAEBGSA-N
IUPAC name(3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide

About Larotrectinib WS

Zemixal lists Larotrectinib WS for laboratories that identify, quantify or control Larotrectinib and its related substances. Identity at a glance (Reference Standard): CAS 1223403-58-4, formula C21H22F2N6O2 and molar mass 428.4 g/mol. It is handled as a solid.

Where it is used

  • Identification & assay
  • Method development & validation
  • QC reference material

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Larotrectinib

See every impurity, metabolite and related compound we list for this API.

Larotrectinib standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Larotrectinib WS
Product nameLarotrectinib WS
Catalogue numberZX-006599
CAS number1223403-58-4
IUPAC name(3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide
Molecular formulaC21H22F2N6O2
Molar mass428.4 g/mol
Exact mass428.1772
GradeReference Standard
Physical formSolid
XLogP31.7
H-bond donors / acceptors2 / 7
Topological polar surface area86 Ų
HS code38229090
InChIKeyNYNZQNWKBKUAII-KBXCAEBGSA-N
SMILESC1C[C@@H](N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CC[C@@H](C4)O)C5=C(C=CC(=C5)F)F
PubChem CID46188928
Synonymslarotrectinib, ARRY 470, LOXO 101, LOXO-101, ARRY-470, Larotrectinib (LOXO-101 free base), Larotrectinib (Standard), Larotrectinib (USAN/INN), ARR Y 470, EX-A1981, example 14 [US8865698 B2]

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.

Pack sizes

Pack sizes of Larotrectinib WS
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Larotrectinib WS

Which CAS number identifies Larotrectinib WS?
Larotrectinib WS is registered under CAS 1223403-58-4. You may also see it listed as larotrectinib, ARRY 470, LOXO 101. Our catalogue number for this item is ZX-006599.
What are the formula and molar mass of Larotrectinib WS?
For Larotrectinib WS, its formula is C21H22F2N6O2 and its molar mass is 428.4 g/mol. The systematic (IUPAC) name is (3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide. InChIKey NYNZQNWKBKUAII-KBXCAEBGSA-N lets you match it in any structure database.
How is Larotrectinib WS used in pharmaceutical QC?
Larotrectinib WS is a characterised reference material linked to Larotrectinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Larotrectinib WS?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Larotrectinib WS?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Larotrectinib WS to my country?
Yes. Larotrectinib WS ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.

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