Leucovorin Calcium Salt Pentahydrate

Name: Leucovorin Calcium Salt Pentahydrate
Brand: Zemixal
SKU: ZX-043888

Reference StandardAvailable on request

Leucovorin Calcium Salt Pentahydrate (CAS 6035-45-6) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes

Leucovorin Calcium Salt Pentahydrate chemical structure

CAS number6035-45-6

FormulaC₂₀H₃₁CaN₇O₁₂

Molar mass601.6 g/mol

Physical formSolid

HS code38229090

InChIKeyNPPBLUASYYNAIG-ZIGBGYJWSA-L

IUPAC namecalcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate;pentahydrate

About Leucovorin Calcium Salt Pentahydrate

Zemixal lists Leucovorin Calcium Salt Pentahydrate for laboratories that identify, quantify or control Folinic Acid and its related substances. For your records (Reference Standard), the material is defined by CAS 6035-45-6, formula C20H31CaN7O12 and molar mass 601.6 g/mol. It is handled as a solid.

Use cases we see most often

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Handling and storage

Hazard communication follows GHS (Danger: H315, H317, H319 and H334). Our SDS lists exposure controls and first-aid measures.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Folinic Acid

See every impurity, metabolite and related compound we list for this API.

Folinic Acid standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Leucovorin Calcium Salt Pentahydrate
Product name	Leucovorin Calcium Salt Pentahydrate
Catalogue number	ZX-043888
CAS number	6035-45-6
IUPAC name	calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate;pentahydrate
Molecular formula	C₂₀H₃₁CaN₇O₁₂
Molar mass	601.6 g/mol
Exact mass	601.1657
Grade	Reference Standard
Physical form	Solid
H-bond donors / acceptors	10 / 15
Topological polar surface area	226 Å²
HS code	38229090
InChIKey	NPPBLUASYYNAIG-ZIGBGYJWSA-L
SMILES	C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2]
PubChem CID	135802074
Synonyms	Leucovorin calcium pentahydrate, Calcium folinate pentahydrate, Calcium folinatc, Wellcovorin, Folinic acid (calcium salt pentahydrate), Leucovorin calcium hydrate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Health hazard

Signal word Danger

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements P233, P260, P261, P264, P264 + P265, P271, P272, P280, P284, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P333 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Leucovorin Calcium Salt Pentahydrate
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Leucovorin Calcium Salt Pentahydrate

Which CAS number identifies Leucovorin Calcium Salt Pentahydrate?

Leucovorin Calcium Salt Pentahydrate is registered under CAS 6035-45-6. You may also see it listed as Leucovorin calcium pentahydrate, Calcium folinate pentahydrate, Calcium folinatc. Our catalogue number for this item is ZX-043888.

What are the formula and molar mass of Leucovorin Calcium Salt Pentahydrate?

For Leucovorin Calcium Salt Pentahydrate, its formula is C20H31CaN7O12 and its molar mass is 601.6 g/mol. InChIKey NPPBLUASYYNAIG-ZIGBGYJWSA-L lets you match it in any structure database.

How is Leucovorin Calcium Salt Pentahydrate used in pharmaceutical QC?

Leucovorin Calcium Salt Pentahydrate is a characterised reference material linked to Folinic Acid. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Leucovorin Calcium Salt Pentahydrate?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Leucovorin Calcium Salt Pentahydrate?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Leucovorin Calcium Salt Pentahydrate to my country?

Yes. Because Leucovorin Calcium Salt Pentahydrate is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Folinic Acid standards

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