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Pharmacopeial Impurities (EP / USP / BP)

Folinic Acid EP Impurity B

Reference StandardAvailable on request

Buy Folinic Acid EP Impurity B (CAS 98814-60-9) from Zemixal: C21H23N7O8, COA and SDS with every lot, worldwide shipping.

Pack sizes
Folinic Acid EP Impurity B chemical structure
CAS number98814-60-9
FormulaC21H23N7O8
Molar mass501.4 g/mol
Physical formSolid
HS code38229090
InChIKeyNQACWOLNMUVBMP-KZUDCZAMSA-N
IUPAC name(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid

About Folinic Acid EP Impurity B

Folinic Acid EP Impurity B belongs to the Folinic Acid reference-standard family in the Zemixal catalogue. For your records (Reference Standard), the material is defined by CAS 98814-60-9, formula C21H23N7O8 and molar mass 501.4 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Safe handling

It carries the GHS signal word Danger (H317 and H334), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Folinic Acid

See every impurity, metabolite and related compound we list for this API.

Folinic Acid standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Folinic Acid EP Impurity B
Product nameFolinic Acid EP Impurity B
Catalogue numberZX-021742
CAS number98814-60-9
IUPAC name(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
Molecular formulaC21H23N7O8
Molar mass501.4 g/mol
Exact mass501.1608
GradeReference Standard
Physical formSolid
XLogP3-1.9
H-bond donors / acceptors6 / 10
Topological polar surface area224 Ų
HS code38229090
InChIKeyNQACWOLNMUVBMP-KZUDCZAMSA-N
SMILESC1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CN(C=O)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID139025760
SynonymsLevofolinate EP Impurity B, Folinic Acid Impurity B, Calcium Levofolinate Pentahydrate - Impurity B, N5,N10-diformyl-tetrahydrofolic acid, 5,10-Diformyl-5,6,7,8-tetrahydro Folic Acid Calcium Salt Hydrate, 5,10-Diformyl-(6S)-tetrahydrofolic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H317May cause an allergic skin reaction
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Folinic Acid EP Impurity B
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Folinic Acid EP Impurity B

Which CAS number identifies Folinic Acid EP Impurity B?
Folinic Acid EP Impurity B is registered under CAS 98814-60-9. You may also see it listed as Levofolinate EP Impurity B, Folinic Acid Impurity B, Calcium Levofolinate Pentahydrate - Impurity B. Our catalogue number for this item is ZX-021742.
What are the formula and molar mass of Folinic Acid EP Impurity B?
For Folinic Acid EP Impurity B, its formula is C21H23N7O8 and its molar mass is 501.4 g/mol. The systematic (IUPAC) name is (2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid. InChIKey NQACWOLNMUVBMP-KZUDCZAMSA-N lets you match it in any structure database.
How is Folinic Acid EP Impurity B used in pharmaceutical QC?
Folinic Acid EP Impurity B is a characterised reference material linked to Folinic Acid. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Folinic Acid EP Impurity B?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Folinic Acid EP Impurity B?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Folinic Acid EP Impurity B to my country?
Yes. Because Folinic Acid EP Impurity B is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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