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Pharmacopeial Impurities (EP / USP / BP)

Lorazepam EP Impurity B

Reference StandardAvailable on request

Lorazepam EP Impurity B (CAS 2848-96-6) supplier Zemixal. Request a quote with price, lead time and documents. Packs from 10 mg.

Pack sizes
Lorazepam EP Impurity B chemical structure
CAS number2848-96-6
FormulaC17H12Cl2N2O3
Molar mass363.2 g/mol
Physical formSolid
HS code38229090
InChIKeyCYDZMDOLVUBPNL-UHFFFAOYSA-N
IUPAC name[7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate

About Lorazepam EP Impurity B

Lorazepam EP Impurity B belongs to the Lorazepam reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 2848-96-6, formula C17H12Cl2N2O3 and molar mass 363.2 g/mol. It is handled as a solid.

Where it is used

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

Classified under GHS with signal word Warning and hazard statements H302, H361, H400 and H410. Read the SDS before first use.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Lorazepam

See every impurity, metabolite and related compound we list for this API.

Lorazepam standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Lorazepam EP Impurity B
Product nameLorazepam EP Impurity B
Catalogue numberZX-036849
CAS number2848-96-6
IUPAC name[7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate
Molecular formulaC17H12Cl2N2O3
Molar mass363.2 g/mol
Exact mass362.0225
GradeReference Standard
Physical formSolid
XLogP33
H-bond donors / acceptors1 / 4
Topological polar surface area67.8 Ų
HS code38229090
InChIKeyCYDZMDOLVUBPNL-UHFFFAOYSA-N
SMILESCC(=O)OC1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3Cl
PubChem CID17836
SynonymsLorazepam Acetate, Lorazepam - Impurity B, 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-, acetic acid [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] ester, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one, Lorazepam Impurity 8, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate, 7-Chloro-5-(2-chlorophenyl)-2-hydroxy-3H-1,4-benzodiazepin-3-yl acetate, 7-chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl acetate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H302Harmful if swallowed
  • H361Suspected of damaging fertility or the unborn child
  • H400Very toxic to aquatic life
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements P203, P264, P270, P273, P280, P301 + P317, P318, P330, P391, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Lorazepam EP Impurity B
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Lorazepam EP Impurity B

Which CAS number identifies Lorazepam EP Impurity B?
Lorazepam EP Impurity B is registered under CAS 2848-96-6. You may also see it listed as Lorazepam Acetate, Lorazepam - Impurity B, 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-. Our catalogue number for this item is ZX-036849.
What are the formula and molar mass of Lorazepam EP Impurity B?
For Lorazepam EP Impurity B, its formula is C17H12Cl2N2O3 and its molar mass is 363.2 g/mol. The systematic (IUPAC) name is [7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate. InChIKey CYDZMDOLVUBPNL-UHFFFAOYSA-N lets you match it in any structure database.
How is Lorazepam EP Impurity B used in pharmaceutical QC?
Lorazepam EP Impurity B is a characterised reference material linked to Lorazepam. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Lorazepam EP Impurity B?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Lorazepam EP Impurity B?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Lorazepam EP Impurity B to my country?
Yes. Because Lorazepam EP Impurity B is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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