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API Reference Standards

Lorlatinib

Reference StandardAvailable on request

Lorlatinib (CAS 1454846-35-5) supplier Zemixal. Request a quote with price, lead time and documents. Packs from 10 mg. Catalogue no. ZX-025439.

Pack sizes
Lorlatinib chemical structure
CAS number1454846-35-5
FormulaC21H19FN6O2
Molar mass406.4 g/mol
Physical formSolid
HS code38229090
InChIKeyIIXWYSCJSQVBQM-LLVKDONJSA-N
IUPAC name(16R)-19-amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10(15),11,13,18,20-octaene-3-carbonitrile

About Lorlatinib

Lorlatinib is supplied by Zemixal as a characterised reference material for Lorlatinib analysis. Key data (Reference Standard): CAS 1454846-35-5, formula C21H19FN6O2 and molar mass 406.4 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Identification & assay
  • Method development & validation
  • QC reference material

Handling and storage

Hazard communication follows GHS (Warning: H341, H361, H373 and H400). Our SDS lists exposure controls and first-aid measures.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Lorlatinib

See every impurity, metabolite and related compound we list for this API.

Lorlatinib standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Lorlatinib
Product nameLorlatinib
Catalogue numberZX-025439
CAS number1454846-35-5
IUPAC name(16R)-19-amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10(15),11,13,18,20-octaene-3-carbonitrile
Molecular formulaC21H19FN6O2
Molar mass406.4 g/mol
Exact mass406.1554
GradeReference Standard
Physical formSolid
XLogP31.5
H-bond donors / acceptors1 / 7
Topological polar surface area110 Ų
HS code38229090
InChIKeyIIXWYSCJSQVBQM-LLVKDONJSA-N
SMILESC[C@@H]1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
PubChem CID71731823
SynonymsPF06463922(Lorlatinib), 4cli, 4clj, EX-A828

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H341Suspected of causing genetic defects
  • H361Suspected of damaging fertility or the unborn child
  • H373May causes damage to organs through prolonged or repeated exposure
  • H400Very toxic to aquatic life
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements P203, P260, P273, P280, P318, P319, P391, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Lorlatinib
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Lorlatinib

Which CAS number identifies Lorlatinib?
Lorlatinib is registered under CAS 1454846-35-5. You may also see it listed as PF06463922(Lorlatinib), 4cli, 4clj. Our catalogue number for this item is ZX-025439.
What are the formula and molar mass of Lorlatinib?
For Lorlatinib, its formula is C21H19FN6O2 and its molar mass is 406.4 g/mol. The systematic (IUPAC) name is (16R)-19-amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10(15),11,13,18,20-octaene-3-carbonitrile. InChIKey IIXWYSCJSQVBQM-LLVKDONJSA-N lets you match it in any structure database.
How is Lorlatinib used in pharmaceutical QC?
Lorlatinib is a characterised reference material linked to Lorlatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Lorlatinib?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Lorlatinib?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Lorlatinib to my country?
Yes. Because Lorlatinib is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Lorlatinib standards

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