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API Impurities

N,N-Bis(2,2,2-trifluoroethyl)nitrous amide

Reference StandardAvailable on request

Buy N,N-Bis(2,2,2-trifluoroethyl)nitrous amide (CAS 625-89-8) from Zemixal: C4H4F6N2O, COA and SDS with every lot, worldwide shipping.

Pack sizes
N,N-Bis(2,2,2-trifluoroethyl)nitrous amide chemical structure
CAS number625-89-8
FormulaC4H4F6N2O
Molar mass210.08 g/mol
Physical formSolid
HS code38229090
InChIKeyYUEXLPFBTMPXCY-UHFFFAOYSA-N
IUPAC nameN,N-bis(2,2,2-trifluoroethyl)nitrous amide

About N,N-Bis(2,2,2-trifluoroethyl)nitrous amide

N,N-Bis(2,2,2-trifluoroethyl)nitrous amide is supplied by Zemixal as a characterised reference material for Upadacitinib analysis. Identity at a glance (Reference Standard): CAS 625-89-8, formula C4H4F6N2O and molar mass 210.08 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Handling and storage

It carries the GHS signal word Danger (H226, H301, H302 and H318), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Upadacitinib

See every impurity, metabolite and related compound we list for this API.

Upadacitinib standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of N,N-Bis(2,2,2-trifluoroethyl)nitrous amide
Product nameN,N-Bis(2,2,2-trifluoroethyl)nitrous amide
Catalogue numberZX-047782
CAS number625-89-8
IUPAC nameN,N-bis(2,2,2-trifluoroethyl)nitrous amide
Molecular formulaC4H4F6N2O
Molar mass210.08 g/mol
Exact mass210.0228
GradeReference Standard
Physical formSolid
XLogP32.1
H-bond donors / acceptors0 / 9
Topological polar surface area32.7 Ų
HS code38229090
InChIKeyYUEXLPFBTMPXCY-UHFFFAOYSA-N
SMILESC(C(F)(F)F)N(CC(F)(F)F)N=O
PubChem CID12267
SynonymsN-Nitrosobis(2,2,2-trifluoroethyl)amine, 2,2,2-trifluoro-N-nitroso-N-(2,2,2-trifluoroethyl)ethanamine, NDEA-F6, N-Nitrosobis(2,2,2-trifluoroethyl) amine, 6-F-Den, Hexafluorodiethylnitrosamine, N-Nitroso-bis(2,2,2-trifluoroethyl)amine, N-Nitroso-2,2,2,2',2',2'-hexafluorodiethylamine, Ethanamine, 2,2,2-trifluoro-N-nitroso-N-(2,2,2-trifluoroethyl)-, N-nitroso-bis-(2,2,2-trifluoroethyl)amine, Nitrosobis(2,2,2-trifluoroethyl)amine, N-

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS02 Flammable
Flammable
GHS05 Corrosive
Corrosive
GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H226Flammable liquid and vapor
  • H301Toxic if swallowed
  • H302Harmful if swallowed
  • H318Causes serious eye damage
  • H351Suspected of causing cancer

Precautionary statements P203, P210, P233, P240, P241, P242, P243, P264, P264 + P265, P270, P280, P301 + P316, P301 + P317, P303 + P361 + P353, P305 + P354 + P338, P317, P318, P321, P330, P370 + P378, P403 + P235, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of N,N-Bis(2,2,2-trifluoroethyl)nitrous amide
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about N,N-Bis(2,2,2-trifluoroethyl)nitrous amide

Which CAS number identifies N,N-Bis(2,2,2-trifluoroethyl)nitrous amide?
N,N-Bis(2,2,2-trifluoroethyl)nitrous amide is registered under CAS 625-89-8. You may also see it listed as N-Nitrosobis(2,2,2-trifluoroethyl)amine, 2,2,2-trifluoro-N-nitroso-N-(2,2,2-trifluoroethyl)ethanamine, NDEA-F6. Our catalogue number for this item is ZX-047782.
What are the formula and molar mass of N,N-Bis(2,2,2-trifluoroethyl)nitrous amide?
For N,N-Bis(2,2,2-trifluoroethyl)nitrous amide, its formula is C4H4F6N2O and its molar mass is 210.08 g/mol. The systematic (IUPAC) name is N,N-bis(2,2,2-trifluoroethyl)nitrous amide. InChIKey YUEXLPFBTMPXCY-UHFFFAOYSA-N lets you match it in any structure database.
How is N,N-Bis(2,2,2-trifluoroethyl)nitrous amide used in pharmaceutical QC?
N,N-Bis(2,2,2-trifluoroethyl)nitrous amide is a characterised reference material linked to Upadacitinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for N,N-Bis(2,2,2-trifluoroethyl)nitrous amide?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with N,N-Bis(2,2,2-trifluoroethyl)nitrous amide?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship N,N-Bis(2,2,2-trifluoroethyl)nitrous amide to my country?
Yes. Because N,N-Bis(2,2,2-trifluoroethyl)nitrous amide is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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