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Pharmacopeial Impurities (EP / USP / BP)

Naproxen EP Impurity B

Reference StandardAvailable on request

Naproxen EP Impurity B (CAS 89617-86-7) supplier Zemixal: C14H13ClO3, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-022234.

Pack sizes
Naproxen EP Impurity B chemical structure
CAS number89617-86-7
FormulaC14H13ClO3
Molar mass264.7 g/mol
Physical formSolid
HS code38229090
InChIKeyRVVAYDHIVLCPBC-QMMMGPOBSA-N
IUPAC name(2S)-2-(5-chloro-6-methoxynaphthalen-2-yl)propanoic acid

About Naproxen EP Impurity B

Analytical teams working on Naproxen use Naproxen EP Impurity B as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 89617-86-7, formula C14H13ClO3 and molar mass 264.7 g/mol. It is handled as a solid.

Where it is used

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Handling and storage

Hazard communication follows GHS (Warning: H302, H315, H319 and H335). Our SDS lists exposure controls and first-aid measures.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Naproxen

See every impurity, metabolite and related compound we list for this API.

Naproxen standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Naproxen EP Impurity B
Product nameNaproxen EP Impurity B
Catalogue numberZX-022234
CAS number89617-86-7
IUPAC name(2S)-2-(5-chloro-6-methoxynaphthalen-2-yl)propanoic acid
Molecular formulaC14H13ClO3
Molar mass264.7 g/mol
Exact mass264.0553
GradeReference Standard
Physical formSolid
XLogP33.8
H-bond donors / acceptors1 / 3
Topological polar surface area46.5 Ų
HS code38229090
InChIKeyRVVAYDHIVLCPBC-QMMMGPOBSA-N
SMILESC[C@@H](C1=CC2=C(C=C1)C(=C(C=C2)OC)Cl)C(=O)O
PubChem CID13075209
Synonyms(S)-5-Chloro Naproxen, Naproxen - Impurity B, 5-Chloronaproxen, (S)-, 5-Chloro naproxen, (S)-, 5-Chloro naproxen, (+)-, 2-Naphthaleneacetic acid, 5-chloro-6-methoxy-alpha-methyl-, (alphaS)-, Naproxen impurity B, Naproxen sodium impurity B, (S)-2-(5-Chloro-6-methoxynaphthalen-2-yl)propanoic acid, (S)-5-Chloro-6-Methoxy-, A-Methyl-2-naphthaleneacetic Acid, (2S)-2-(5-Chloro-6-methoxynaphthalen-2-yl)propanoic Acid (5-Chloronaproxen), (2S)-2-(5-chloro-6-methoxy-2-naphthyl)propanoic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H411Toxic to aquatic life with long lasting effects

Precautionary statements P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Naproxen EP Impurity B
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Naproxen EP Impurity B

Which CAS number identifies Naproxen EP Impurity B?
Naproxen EP Impurity B is registered under CAS 89617-86-7. You may also see it listed as (S)-5-Chloro Naproxen, Naproxen - Impurity B, 5-Chloronaproxen, (S)-. Our catalogue number for this item is ZX-022234.
What are the formula and molar mass of Naproxen EP Impurity B?
For Naproxen EP Impurity B, its formula is C14H13ClO3 and its molar mass is 264.7 g/mol. The systematic (IUPAC) name is (2S)-2-(5-chloro-6-methoxynaphthalen-2-yl)propanoic acid. InChIKey RVVAYDHIVLCPBC-QMMMGPOBSA-N lets you match it in any structure database.
How is Naproxen EP Impurity B used in pharmaceutical QC?
Naproxen EP Impurity B is a characterised reference material linked to Naproxen. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Naproxen EP Impurity B?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Naproxen EP Impurity B?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Naproxen EP Impurity B to my country?
Yes. Because Naproxen EP Impurity B is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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