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API Reference Standards

Nebivolol

Reference StandardAvailable on request

Nebivolol (CAS 118457-14-0) supplier Zemixal. Request a quote with price, lead time and documents. Exported from India with full paperwork.

Pack sizes
Nebivolol chemical structure
CAS number118457-14-0
FormulaC22H25F2NO4
Molar mass405.4 g/mol
Physical formSolid
HS code38229090
InChIKeyKOHIRBRYDXPAMZ-UHFFFAOYSA-N
IUPAC name1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol

About Nebivolol

Analytical teams working on Nebivolol use Nebivolol as a qualified comparison standard. Identity at a glance (Reference Standard): CAS 118457-14-0, formula C22H25F2NO4 and molar mass 405.4 g/mol. It is handled as a solid.

Typical applications

  • Identification & assay
  • Method development & validation
  • QC reference material

Safe handling

It carries the GHS signal word Warning (H302, H315, H319 and H332), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Nebivolol

See every impurity, metabolite and related compound we list for this API.

Nebivolol standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Nebivolol
Product nameNebivolol
Catalogue numberZX-022243
CAS number118457-14-0
IUPAC name1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol
Molecular formulaC22H25F2NO4
Molar mass405.4 g/mol
Exact mass405.1752
GradeReference Standard
Physical formSolid
XLogP33
H-bond donors / acceptors3 / 7
Topological polar surface area71 Ų
HS code38229090
InChIKeyKOHIRBRYDXPAMZ-UHFFFAOYSA-N
SMILESC1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
PubChem CID71301
SynonymsRel-Nebivolol, Nebivolol (R,S,S,S), Nebivolol L Isomer, Narbivolol, dl-Nebivolol, nebibolol, Hydrochloride, Nebivolol, alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro)-2H-1-benzopyran-2-methanol, (Rac)-Nebivolol, 2,2'-Azanediylbis(1-(6-fluorochroman-2-yl)ethanol), 1-(6-fluorochroman-2-yl)-2-[[2-(6-fluorochroman-2-yl)-2-hydroxy-ethyl]amino]ethanol, alpha,alpha'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Warning

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H335May cause respiratory irritation
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Nebivolol
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Nebivolol

Which CAS number identifies Nebivolol?
Nebivolol is registered under CAS 118457-14-0. You may also see it listed as Rel-Nebivolol, Nebivolol (R,S,S,S), Nebivolol L Isomer. Our catalogue number for this item is ZX-022243.
What are the formula and molar mass of Nebivolol?
For Nebivolol, its formula is C22H25F2NO4 and its molar mass is 405.4 g/mol. The systematic (IUPAC) name is 1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol. InChIKey KOHIRBRYDXPAMZ-UHFFFAOYSA-N lets you match it in any structure database.
How is Nebivolol used in pharmaceutical QC?
Nebivolol is a characterised reference material linked to Nebivolol. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Nebivolol?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Nebivolol?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Nebivolol to my country?
Yes. Because Nebivolol is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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