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API Reference Standards

Nilotinib

Reference StandardIn stock

Order Nilotinib (CAS 641571-10-0) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery. Catalogue no. ZX-006681.

Pack sizes
Nilotinib chemical structure
CAS number641571-10-0
FormulaC28H22F3N7O
Molar mass529.5 g/mol
Physical formSolid
HS code38229090
InChIKeyHHZIURLSWUIHRB-UHFFFAOYSA-N
IUPAC name4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide

About Nilotinib

Nilotinib belongs to the Nilotinib reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 641571-10-0, formula C28H22F3N7O and molar mass 529.5 g/mol. It is handled as a solid.

Where it is used

  • Identification & assay
  • Method development & validation
  • QC reference material

Handling and storage

It carries the GHS signal word Danger (H361, H372, H373 and H400), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Nilotinib

See every impurity, metabolite and related compound we list for this API.

Nilotinib standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Nilotinib
Product nameNilotinib
Catalogue numberZX-006681
CAS number641571-10-0
Other CAS numbers923288-95-3, 923288-90-8
IUPAC name4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Molecular formulaC28H22F3N7O
Molar mass529.5 g/mol
Exact mass529.1838
GradeReference Standard
Physical formSolid
XLogP34.9
H-bond donors / acceptors2 / 9
Topological polar surface area97.6 Ų
HS code38229090
InChIKeyHHZIURLSWUIHRB-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
PubChem CID644241
SynonymsTasigna, AMN 107, AMN-107, AMN 107 Base, Nilotinib (AMN-107), Nilotinib free base, 641571-10-0 (free base), Nilotinib (Standard), 3gp0, AMN 107 Base Form, Nilotinib (USAN/INN), Nilotinib - Bio-X trade mark

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Danger

  • H361Suspected of damaging fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure
  • H373May causes damage to organs through prolonged or repeated exposure
  • H400Very toxic to aquatic life
  • H410Very toxic to aquatic life with long lasting effects
  • H413May cause long lasting harmful effects to aquatic life

Precautionary statements P203, P260, P264, P270, P273, P280, P318, P319, P391, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Nilotinib
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request
500 mgQuoted on request
1 gQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Nilotinib

Which CAS number identifies Nilotinib?
Nilotinib is registered under CAS 641571-10-0. You may also see it listed as Tasigna, AMN 107, AMN-107. Our catalogue number for this item is ZX-006681.
What are the formula and molar mass of Nilotinib?
For Nilotinib, its formula is C28H22F3N7O and its molar mass is 529.5 g/mol. The systematic (IUPAC) name is 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide. InChIKey HHZIURLSWUIHRB-UHFFFAOYSA-N lets you match it in any structure database.
How is Nilotinib used in pharmaceutical QC?
Nilotinib is a characterised reference material linked to Nilotinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Nilotinib?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Nilotinib?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Nilotinib to my country?
Yes. Because Nilotinib is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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