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API Process Intermediates & Related Compounds

Sacubitril

Reference StandardIn stock

Buy Sacubitril (CAS 149709-62-6) from Zemixal. Request a quote with price, lead time and documents. Catalogue no. ZX-012842.

Pack sizes
Sacubitril chemical structure
CAS number149709-62-6
FormulaC24H29NO5
Molar mass411.5 g/mol
Physical formSolid
HS code2933
Purity99%
InChIKeyPYNXFZCZUAOOQC-UTKZUKDTSA-N
IUPAC name4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid

About Sacubitril

Zemixal supplies Sacubitril within its pharma Intermediates & Building Blocks portfolio. Identity at a glance (Reference Standard): CAS 149709-62-6, formula C24H29NO5 and molar mass 411.5 g/mol. It is handled as a solid.

Typical applications

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Storage and safety notes

Classified under GHS with signal word Warning and hazard statements H317 and H319. Read the SDS before first use.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. Every shipment includes a batch certificate of analysis and a 16-section SDS. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Sacubitril

See every impurity, metabolite and related compound we list for this API.

Sacubitril standards

Typical uses

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Applications

Specifications and identifiers

Specifications of Sacubitril
Product nameSacubitril
Catalogue numberZX-012842
CAS number149709-62-6
Other CAS numbers1369773-39-6, 149690-05-1, 565453-99-8
IUPAC name4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid
Molecular formulaC24H29NO5
Molar mass411.5 g/mol
Exact mass411.2046
GradeReference Standard
Purity / assay99%
Physical formSolid
XLogP33.7
H-bond donors / acceptors2 / 5
Topological polar surface area92.7 Ų
HS code2933
InChIKeyPYNXFZCZUAOOQC-UTKZUKDTSA-N
SMILESCCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O
PubChem CID9811834
SynonymsAHU 377, (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester, 3-{[(2S,4R)-5-Ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]carbamoyl}propanoic acid, AHU-377, (2R,4S)-5-(biphenyl-4-yl)-4-((3-carboxypropionyl)amino)-2-methylpentanoic acid ethyl ester, Sacubitril (JAN/USAN/INN), Sacubitril - Bio-X trade mark, (2R,4S)-5-biphenyl-4-yl-4-(3-carboxy-propionylamino)-2-methyl-pentanoic acid ethyl ester, (2R,4S)-5-Biphenyl-4-yl-4-(3-carboxypropionylamino)-2-methylpentanoic acid ethyl ester, 4-[[(2S,4R)-1-(4-Biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentyl]amino]-4-oxobutanoic Acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H317May cause an allergic skin reaction
  • H319Causes serious eye irritation

Precautionary statements P261, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P321, P333 + P317, P337 + P317, P362 + P364, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Sacubitril
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Sacubitril

Which CAS number identifies Sacubitril?
Sacubitril is registered under CAS 149709-62-6. You may also see it listed as AHU 377, (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester, 3-{[(2S,4R)-5-Ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]carbamoyl}propanoic acid. Our catalogue number for this item is ZX-012842.
What are the formula and molar mass of Sacubitril?
For Sacubitril, its formula is C24H29NO5 and its molar mass is 411.5 g/mol. The systematic (IUPAC) name is 4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid. InChIKey PYNXFZCZUAOOQC-UTKZUKDTSA-N lets you match it in any structure database.
How is Sacubitril used in pharmaceutical QC?
Sacubitril is a characterised reference material linked to Sacubitril. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Sacubitril?
This listing is Reference Standard grade with 99% purity. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Sacubitril?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Sacubitril to my country?
Yes. Because Sacubitril is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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