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Pharmacopeial Impurities (EP / USP / BP)

Spironolactone EP Impurity F

Reference StandardAvailable on request

Order Spironolactone EP Impurity F (CAS 976-71-6) online at Zemixal: C22H28O3, COA and SDS with every lot, worldwide shipping.

Pack sizes
Spironolactone EP Impurity F chemical structure
CAS number976-71-6
FormulaC22H28O3
Molar mass340.5 g/mol
Physical formSolid
HS code38229090
InChIKeyUJVLDDZCTMKXJK-WNHSNXHDSA-N
IUPAC name(8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione

About Spironolactone EP Impurity F

Spironolactone EP Impurity F belongs to the Spironolactone reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 976-71-6, formula C22H28O3 and molar mass 340.5 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

Hazard communication follows GHS (Warning: H312, H332, H351 and H361). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Spironolactone

See every impurity, metabolite and related compound we list for this API.

Spironolactone standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Spironolactone EP Impurity F
Product nameSpironolactone EP Impurity F
Catalogue numberZX-027015
CAS number976-71-6
IUPAC name(8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
Molecular formulaC22H28O3
Molar mass340.5 g/mol
Exact mass340.2038
GradeReference Standard
Physical formSolid
XLogP32.7
H-bond donors / acceptors0 / 3
Topological polar surface area43.4 Ų
HS code38229090
InChIKeyUJVLDDZCTMKXJK-WNHSNXHDSA-N
SMILESC[C@]12CCC(=O)C=C1C=C[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]45CCC(=O)O5)C
PubChem CID13789
SynonymsCanrenone, Spironolactone - Impurity F, Aldadiene, Spironolactone metabolite m1, Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone (17alpha)-, Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone, (17alpha)-, Phanurane, Canrenone (USAN), 17-Hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactone, Aldadiene (VAN), 20-Spiroxa-4,6-diene-3,21-dione, 3',4'-Dihydrospiro[androst-4,6-diene-17,2'(5'H)-furan]-3,5'-dione (Canrenone)

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H312Harmful in contact with skin
  • H332Harmful if inhaled
  • H351Suspected of causing cancer
  • H361Suspected of damaging fertility or the unborn child
  • H373May causes damage to organs through prolonged or repeated exposure
  • H411Toxic to aquatic life with long lasting effects
  • H412Harmful to aquatic life with long lasting effects

Precautionary statements P203, P260, P261, P271, P273, P280, P302 + P352, P304 + P340, P317, P318, P319, P321, P362 + P364, P391, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Spironolactone EP Impurity F
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Spironolactone EP Impurity F

Which CAS number identifies Spironolactone EP Impurity F?
Spironolactone EP Impurity F is registered under CAS 976-71-6. You may also see it listed as Canrenone, Spironolactone - Impurity F, Aldadiene. Our catalogue number for this item is ZX-027015.
What are the formula and molar mass of Spironolactone EP Impurity F?
For Spironolactone EP Impurity F, its formula is C22H28O3 and its molar mass is 340.5 g/mol. The systematic (IUPAC) name is (8R,9S,10R,13S,14S,17R)-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione. InChIKey UJVLDDZCTMKXJK-WNHSNXHDSA-N lets you match it in any structure database.
How is Spironolactone EP Impurity F used in pharmaceutical QC?
Spironolactone EP Impurity F is a characterised reference material linked to Spironolactone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Spironolactone EP Impurity F?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Spironolactone EP Impurity F?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Spironolactone EP Impurity F to my country?
Yes. Because Spironolactone EP Impurity F is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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