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API Impurities

Thiophosgene

Reference StandardAvailable on request

Buy Thiophosgene (CAS 463-71-8) from Zemixal: CCl2S, COA and SDS with every lot, worldwide shipping. Packs from 10 mg. Part of our API Impurities range.

Pack sizes
Thiophosgene chemical structure
CAS number463-71-8
FormulaCCl2S
Molar mass114.98 g/mol
Physical formSolid
HS code38229090
InChIKeyZWZVWGITAAIFPS-UHFFFAOYSA-N
IUPAC namethiocarbonyl dichloride

About Thiophosgene

Thiophosgene is supplied by Zemixal as a characterised reference material for Tretinoin analysis. For your records (Reference Standard), the material is defined by CAS 463-71-8, formula CCl2S and molar mass 114.98 g/mol. It is handled as a solid.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Handling and storage

Hazard communication follows GHS (Danger: H302, H315, H319 and H331). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Tretinoin

See every impurity, metabolite and related compound we list for this API.

Tretinoin standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Thiophosgene
Product nameThiophosgene
Catalogue numberZX-043610
CAS number463-71-8
IUPAC namethiocarbonyl dichloride
Molecular formulaCCl2S
Molar mass114.98 g/mol
Exact mass113.9098
GradeReference Standard
Physical formSolid
XLogP32.4
H-bond donors / acceptors0 / 1
Topological polar surface area32.1 Ų
HS code38229090
InChIKeyZWZVWGITAAIFPS-UHFFFAOYSA-N
SMILESC(=S)(Cl)Cl
PubChem CID10040
SynonymsCarbonothioic dichloride, Thiocarbonyl chloride, Carbon chlorosulfide, Dichlorothiocarbonyl, Thiocarbonic dichloride, Phosgene, thio-, Carbonyl chloride, thio-, Carbonic dichloride, thio-, Thiophosgene [UN2474] [Poison], Carbonothioicdichloride

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity

Signal word Danger

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H331Toxic if inhaled
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Thiophosgene
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Thiophosgene

Which CAS number identifies Thiophosgene?
Thiophosgene is registered under CAS 463-71-8. You may also see it listed as Carbonothioic dichloride, Thiocarbonyl chloride, Carbon chlorosulfide. Our catalogue number for this item is ZX-043610.
What are the formula and molar mass of Thiophosgene?
For Thiophosgene, its formula is CCl2S and its molar mass is 114.98 g/mol. The systematic (IUPAC) name is thiocarbonyl dichloride. InChIKey ZWZVWGITAAIFPS-UHFFFAOYSA-N lets you match it in any structure database.
How is Thiophosgene used in pharmaceutical QC?
Thiophosgene is a characterised reference material linked to Tretinoin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Thiophosgene?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Thiophosgene?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Thiophosgene to my country?
Yes. Because Thiophosgene is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

Other grades with CAS 463-71-8

More Tretinoin standards

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