Impurity reference standards
Tretinoin impurity standards
78 characterised compounds linked to Tretinoin are catalogued here, from named pharmacopoeial impurities to synthesis intermediates and breakdown products. Highlights of the range are 2 pharmacopoeial impurities, 2 nitrosamines, 6 metabolites or hydroxylated analogues and 1 degradation product.
78reference materials
2pharmacopoeial
2nitrosamines
6metabolites
Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. Laboratories use them to validate related-substance methods, set specification limits under ICH Q3A and Q3B, and identify unknown peaks in stability samples. The nitrosamine entries support ICH M7 risk assessments and confirmatory testing at trace levels.
By impurity type
Pharmacopoeial2EP, USP, BP or JP named impurities
Nitrosamines2N-nitroso impurities for ICH M7 work
Metabolites6Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products
Counts are based on product names. One compound can fall into more than one type.
All Tretinoin reference materials
1–60 of 78 standards
{4-[3-(Ethylcarbamoyl)phenyl]phenyl}acetic acid
- CAS
- 1375069-21-8
- Formula
- C17H17NO3
- MW
- 283.32 g/mol
ZX-043543
1-[(S)-O-(5-Isoquinolinesulfonyl)-N-methyltyrosyl]-4-phenyl-piperazine
- CAS
- 1391068-10-2
- Formula
- C29H30N4O4S
- MW
- 530.6 g/mol
ZX-043495
2-(N-Methyl-2-pyrrolidinyl)ethyl Chloride Hydrochloride
- CAS
- 56824-22-7
- Formula
- C7H15Cl2N
- MW
- 184.1 g/mol
ZX-039754
2,6-Dibromo-4-(trifluoromethylsulfonyl)toluene
- CAS
- 1150271-31-0
- Formula
- C8H5Br2F3O2S
- MW
- 381.99 g/mol
ZX-043527
4-(2-Keto-3-methyl-1-benzimidazolinyl)piperidine
- CAS
- 53786-10-0
- Formula
- C13H17N3O
- MW
- 231.29 g/mol
ZX-043503
4-(4-Hydroxy-4-methylpentyl)cyclohex-3-enecarbaldehyde
- CAS
- 31906-04-4
- Formula
- C13H22O2
- MW
- 210.31 g/mol
ZX-041755
4-[4-(Ethylcarbamoyl)-3-fluorophenyl]phenylacetic acid
- CAS
- 1334500-11-6
- Formula
- C17H16FNO3
- MW
- 301.31 g/mol
ZX-043544
Ethyl 4-Isopropyl-4-piperidinecarboxylate Hydrochloride
- CAS
- 1186663-19-3
- Formula
- C11H22ClNO2
- MW
- 235.75 g/mol
ZX-043485
Ethyl 4,5,6,7-tetrahydro-1H-indole-2-carboxylate
- CAS
- 65880-18-4
- Formula
- C11H15NO2
- MW
- 193.24 g/mol
ZX-043486
Lithium (5-cyanopyridin-2-yl)triisopropoxyborate
- CAS
- 1048030-52-9
- Formula
- C15H24BLiN2O3
- MW
- 298.1 g/mol
ZX-043586
Lithium (5-fluoropyridin-2-yl)trihydroxyborate
- CAS
- 1393822-88-2
- Formula
- C5H6BFLiNO3
- MW
- 164.9 g/mol
ZX-043590
Lithium [6-(1,3-dioxolan-2-yl)pyridin-2-yl]triisopropoxyborate
- CAS
- 1048030-50-7
- Formula
- C17H29BLiNO5
- MW
- 345.2 g/mol
ZX-043589
Lithium trihydroxy(4-(trifluoromethyl)pyridin-2-yl)borate
- CAS
- 1393822-85-9
- Formula
- C6H6BF3LiNO3
- MW
- 214.9 g/mol
ZX-043592
Lithium trihydroxy(6-(trifluoromethyl)pyridin-2-yl)borate
- CAS
- 1393822-87-1
- Formula
- C6H6BF3LiNO3
- MW
- 214.9 g/mol
ZX-043593
Lithium triisopropoxy(5-methylthiophen-2-yl)borate
- CAS
- 1256364-33-6
- Formula
- C14H26BLiO3S
- MW
- 292.2 g/mol
ZX-043594
Lithium triisopropyl 2-(4-methylpyridyl)borate
- CAS
- 1202220-93-6
- Formula
- C15H27BLiNO3
- MW
- 287.2 g/mol
ZX-043602
Lithium triisopropyl 2-(5-chloropyridyl)borate
- CAS
- 1256364-35-8
- Formula
- C14H24BClLiNO3
- MW
- 307.6 g/mol
ZX-043596
Lithium triisopropyl 2-(5-fluoropyridyl)borate
- CAS
- 1048030-49-4
- Formula
- C14H24BFLiNO3
- MW
- 291.1 g/mol
ZX-043598
Lithium triisopropyl 2-(5-methoxypyridyl)borate
- CAS
- 1256364-38-1
- Formula
- C15H27BLiNO4
- MW
- 303.2 g/mol
ZX-043600
Questions
Tretinoin impurities, answered
How many Tretinoin impurity standards does Zemixal list?
The catalogue currently lists 78 compounds for Tretinoin, including 2 pharmacopoeial impurities, 2 nitrosamines, 6 metabolites or hydroxylated analogues and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Tretinoin impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Tretinoin impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
Do you supply Tretinoin nitrosamine impurities?
Yes. 2 N-nitroso compounds are listed for Tretinoin. They are used for confirmatory testing and method validation in line with ICH M7 and the nitrosamine guidance from the major regulators.