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Impurity reference standards

Carfilzomib impurity standards

38 characterised compounds linked to Carfilzomib are catalogued here, from named pharmacopoeial impurities to synthesis intermediates and breakdown products. Highlights of the range are 1 isotope-labelled standard, 1 metabolite or hydroxylated analogue and 1 degradation product.

38reference materials
1isotope labelled
1metabolites
1degradants
Carfilzomib WS structure
Parent API

Carfilzomib WS

CAS
868540-17-4
Formula
C40H57N5O7
MW
719.9 g/mol
Code
ZX-006452

Batches are supplied with a certificate of analysis, and the supporting spectra can be sent ahead of a purchase order so your QA team can review them. Typical uses are method development and validation, relative response factor work, forced degradation studies and the impurity sections of ANDA, DMF or CEP filings.

By impurity type

Isotope labelled1Deuterated, 13C or 15N internal standards
Metabolites1Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products

Counts are based on product names. One compound can fall into more than one type.

All Carfilzomib reference materials

1–38 of 38 standards
Questions

Carfilzomib impurities, answered

How many Carfilzomib impurity standards does Zemixal list?
The catalogue currently lists 38 compounds for Carfilzomib, including 1 isotope-labelled standard, 1 metabolite or hydroxylated analogue and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Carfilzomib impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Carfilzomib impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
Are isotope-labelled Carfilzomib standards available?
Yes. 1 stable-isotope labelled compound is listed, suitable as internal standards for LC-MS bioanalysis and trace impurity quantitation.
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