Impurity reference standards
Cobicistat impurity standards
This page brings together 15 Cobicistat related compounds that analytical teams use to identify, quantify and control impurities in the active ingredient and the finished dosage form. The range includes 1 metabolite or hydroxylated analogue and 1 degradation product.
15reference materials
1metabolites
1degradants
Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions.
By impurity type
Metabolites1Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products
Counts are based on product names. One compound can fall into more than one type.
All Cobicistat reference materials
1–15 of 15 standards
(2R,5R)-1,6-Diphenylhexane-2,5-diamine Dihydrochloride
- CAS
- 1247119-31-8
- Formula
- C18H26Cl2N2
- MW
- 341.3 g/mol
ZX-011806
(S)-(-)-Alpha-Amino-gamma-butyrolactone hydrobromide
- CAS
- 15295-77-9
- Formula
- C4H8BrNO2
- MW
- 182.02 g/mol
ZX-034408
(S)-1-((2-Isopropylthiazol-4-yl)methyl)-1-methyl-3-(2-oxotetrahydrofuran-3-yl)urea
- CAS
- 1004316-93-1
- Formula
- C13H19N3O3S
- MW
- 297.38 g/mol
ZX-028728
2-(4-((Methylamino)methyl)thiazol-2-yl)propan-2-ol
- CAS
- 1051463-24-1
- Formula
- C8H14N2OS
- MW
- 186.28 g/mol
ZX-028726
Cobicistat on Colloidal silicon Dioxide Related Compound 7
- CAS
- 1004316-56-6
- Formula
- C28H30N4O4S2
- MW
- 550.7 g/mol
ZX-004544
Ethyl(S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanoate oxalate
- CAS
- 1247119-35-2
- Formula
- C19H32N4O4S
- MW
- 412.5 g/mol
ZX-028725
Thiazol-5-Ylmethyl ((2R,5R)-5-((S)-2-Amino-4-morpholinobutanamido)-1,6-diphenylhexan-2-yl)Carbamate
- CAS
- 1051463-15-0
- Formula
- C31H41N5O4S
- MW
- 579.8 g/mol
ZX-028729
Thiazol-5-ylmethyl ((2S,5S)-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-4-morpholinobutanamido)-1,6-diphenylhexan-2-yl)carbamate
- CAS
- 2230789-82-7
- Formula
- C40H53N7O5S2
- MW
- 776 g/mol
ZX-024046
Questions
Cobicistat impurities, answered
What Cobicistat reference materials are available?
The catalogue currently lists 15 compounds for Cobicistat, including 1 metabolite or hydroxylated analogue and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Cobicistat impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Cobicistat impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.