8-[2-(Diphenylmethoxy)-N-methylethylamino]-1,3-dimethylxanthine
- CAS
- 33120-34-2
- Formula
- C23H25N5O3
- MW
- 419.5 g/mol
ZX-024297
Impurity reference standards
Dimenhydrinate impurity standards
This page brings together 6 Dimenhydrinate related compounds that analytical teams use to identify, quantify and control impurities in the active ingredient and the finished dosage form. The range includes 2 pharmacopoeial impurities, 1 nitrosamine and 1 metabolite or hydroxylated analogue.
6reference materials
2pharmacopoeial
1nitrosamines
1metabolites
Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions. For nitrosamine risk evaluation, the N-nitroso standards allow confirmatory LC-MS testing against the acceptable intake limits.
By impurity type
Pharmacopoeial2EP, USP, BP or JP named impurities
Nitrosamines1N-nitroso impurities for ICH M7 work
Metabolites1Hydroxy, desmethyl and conjugated forms
Counts are based on product names. One compound can fall into more than one type.
All Dimenhydrinate reference materials
1–6 of 6 standards
8-[N-(2-Diphenylmethoxyethyl)-N,N-dimethylaminium]-1,3-dimethylxanthine Inner Salt
- CAS
- 64487-94-1
- Formula
- C24H27N5O3
- MW
- 433.5 g/mol
ZX-029005
Questions
Dimenhydrinate impurities, answered
What Dimenhydrinate reference materials are available?
The catalogue currently lists 6 compounds for Dimenhydrinate, including 2 pharmacopoeial impurities, 1 nitrosamine and 1 metabolite or hydroxylated analogue. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Dimenhydrinate impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Dimenhydrinate impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
Do you supply Dimenhydrinate nitrosamine impurities?
Yes. 1 N-nitroso compound is listed for Dimenhydrinate. They are used for confirmatory testing and method validation in line with ICH M7 and the nitrosamine guidance from the major regulators.