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Impurity reference standards

Dorzolamide impurity standards

Zemixal lists 20 reference materials related to Dorzolamide, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 4 pharmacopoeial impurities, 2 metabolites or hydroxylated analogues and 1 degradation product.

20reference materials
4pharmacopoeial
2metabolites
1degradants

Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. Laboratories use them to validate related-substance methods, set specification limits under ICH Q3A and Q3B, and identify unknown peaks in stability samples.

By impurity type

Pharmacopoeial4EP, USP, BP or JP named impurities
Metabolites2Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products

Counts are based on product names. One compound can fall into more than one type.

All Dorzolamide reference materials

1–20 of 20 standards
Questions

Dorzolamide impurities, answered

How many Dorzolamide impurity standards does Zemixal list?
The catalogue currently lists 20 compounds for Dorzolamide, including 4 pharmacopoeial impurities, 2 metabolites or hydroxylated analogues and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Dorzolamide impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Dorzolamide impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
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