Impurity reference standards
Edoxaban impurity standards
Zemixal lists 71 reference materials related to Edoxaban, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 1 pharmacopoeial impurity, 5 metabolites or hydroxylated analogues and 2 degradation products.
71reference materials
1pharmacopoeial
5metabolites
2degradants
Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. Laboratories use them to validate related-substance methods, set specification limits under ICH Q3A and Q3B, and identify unknown peaks in stability samples.
By impurity type
Pharmacopoeial1EP, USP, BP or JP named impurities
Metabolites5Hydroxy, desmethyl and conjugated forms
Degradants2N-oxides, dimers, lactones and breakdown products
Counts are based on product names. One compound can fall into more than one type.
All Edoxaban reference materials
1–60 of 71 standards
(1S,3R,4S)-4-Amino-3-(Boc-amino)-cyclohexane-carboxylic acid ethyl ester
- CAS
- 480449-84-1
- Formula
- C14H26N2O4
- MW
- 286.37 g/mol
ZX-033361
(1S,3R,4S)-4-Azido-3-(tertbutoxycarbonylamino) cyclohexane carboxylic acid
- CAS
- 365997-67-7
- Formula
- C12H20N4O4
- MW
- 284.31 g/mol
ZX-029153
1S 3r 4r 3 tert butoxycarbonyl amino 4 methylsulfonyl oxy cyclohexanecarboxylic acid ethyl ester
- CAS
- 365997-36-0
- Formula
- C15H27NO7S
- MW
- 365.4 g/mol
ZX-029150
5-Methyl-4,5,6,7- tetrahydrothiazolo [5,4-c]pyridine-2-carboxylic acid hydrochloride
- CAS
- 720720-96-7
- Formula
- C8H11ClN2O2S
- MW
- 234.7 g/mol
ZX-021515
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 4-methylbenzenesulfonate
- CAS
- 852291-40-8
- Formula
- C14H18N2O3S2
- MW
- 326.43 g/mol
ZX-039079
5-Methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-amine
- CAS
- 17899-48-8
- Formula
- C7H11N3S
- MW
- 169.25 g/mol
ZX-039080
Benzyl tert-butyl ((1S,2R,4S)-4-(dimethylcarbamoyl)cyclohexane-1,2-diyl)dicarbamate
- CAS
- 365998-35-2
- Formula
- C22H33N3O5
- MW
- 419.5 g/mol
ZX-029149
Carbamicacid,N-[(1S,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-, 1,1-dimethylethyl ester
- CAS
- 2081883-52-3
- Formula
- C14H27N3O3
- MW
- 285.38 g/mol
ZX-024445
Edoxaban thiazol-pyridine-2-carboxylic acid impurity
- CAS
- 1190987-12-2
- Formula
- C7H8N2O2S
- MW
- 184.22 g/mol
ZX-029155
Ethyl (1R,3S,4R)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxycyclohexane-1-carboxylate
- CAS
- 1392745-22-0
- Formula
- C14H25NO5
- MW
- 287.35 g/mol
ZX-033363
Ethyl (1S,3R,4R)-3-{[(tert-butoxy)carbonyl]amino}-4-hydroxycyclohexane-1-carboxylate
- CAS
- 365997-33-7
- Formula
- C14H25NO5
- MW
- 287.35 g/mol
ZX-033365
Ethyl 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetate
- CAS
- 480450-85-9
- Formula
- C21H31N5O5S
- MW
- 465.6 g/mol
ZX-024432
N-(5-Chloropyridin-2-yl)oxalamic acid ethyl ester
- CAS
- 349125-08-2
- Formula
- C9H9ClN2O3
- MW
- 228.63 g/mol
ZX-029165
N1-((1S, 2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)- N2-(5-chloro pyridin-2-yl)oxalamide
- CAS
- 480452-37-7
- Formula
- C16H22ClN5O3
- MW
- 367.8 g/mol
ZX-029163
tert-Butyl ((1R,2R,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate Oxalate
- CAS
- 1928729-31-0
- Formula
- C16H29N3O7
- MW
- 375.42 g/mol
ZX-024437
tert-Butyl ((1R,2R,5S)-5-(dimethylcarbamoyl)-2-hydroxycyclohexyl)carbamate
- CAS
- 929693-30-1
- Formula
- C14H26N2O4
- MW
- 286.37 g/mol
ZX-029166
Questions
Edoxaban impurities, answered
How many Edoxaban impurity standards does Zemixal list?
The catalogue currently lists 71 compounds for Edoxaban, including 1 pharmacopoeial impurity, 5 metabolites or hydroxylated analogues and 2 degradation products. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Edoxaban impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Edoxaban impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.