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Impurity reference standards

Eltrombopag impurity standards

Zemixal lists 22 reference materials related to Eltrombopag, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 1 isotope-labelled standard, 3 metabolites or hydroxylated analogues and 1 degradation product.

22reference materials
1isotope labelled
3metabolites
1degradants
Eltrombopag structure
Parent API

Eltrombopag

CAS
496775-61-2
Formula
C25H22N4O4
MW
442.5 g/mol
Code
ZX-006526

Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions.

By impurity type

Isotope labelled1Deuterated, 13C or 15N internal standards
Metabolites3Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products

Counts are based on product names. One compound can fall into more than one type.

All Eltrombopag reference materials

1–22 of 22 standards
Questions

Eltrombopag impurities, answered

How many Eltrombopag impurity standards does Zemixal list?
The catalogue currently lists 22 compounds for Eltrombopag, including 1 isotope-labelled standard, 3 metabolites or hydroxylated analogues and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Eltrombopag impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Eltrombopag impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
Are isotope-labelled Eltrombopag standards available?
Yes. 1 stable-isotope labelled compound is listed, suitable as internal standards for LC-MS bioanalysis and trace impurity quantitation.
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