Impurity reference standards

Iptacopan impurity standards

This page brings together 10 Iptacopan related compounds that analytical teams use to identify, quantify and control impurities in the active ingredient and the finished dosage form. The range includes 1 metabolite or hydroxylated analogue.

10reference materials

1metabolites

Parent API

Iptacopan

CAS: 1644670-37-0
Formula: C₂₅H₃₀N₂O₄
MW: 422.5 g/mol
Code: ZX-006579

Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions.

By impurity type

Metabolites1Hydroxy, desmethyl and conjugated forms

Counts are based on product names. One compound can fall into more than one type.

All Iptacopan reference materials

1–10 of 10 standards

4-((2R,4R)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid

CAS: 1644670-39-2
Formula: C₂₅H₃₀N₂O₄
MW: 422.5 g/mol

ZX-021884

4-((2S,4S)-4-Hydroxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid

CAS: 1644670-02-9
Formula: C₂₃H₂₆N₂O₄
MW: 394.5 g/mol

ZX-025155

Iptacopan

CAS: 1644670-37-0
Formula: C₂₅H₃₀N₂O₄
MW: 422.5 g/mol

ZX-006579

Iptacopan Hydrochloride

CAS: 1646321-63-2
Formula: C₂₅H₃₁ClN₂O₄
MW: 459 g/mol

ZX-006580

Iptacopan Impurtiy 1

CAS: 2361158-02-1
Formula: C₃₁H₄₀N₂O₆
MW: 536.7 g/mol

ZX-047990

Methyl 4-((2R,4R)-4-ethoxypiperidin-2-yl)benzoate

CAS: 2891579-89-6
Formula: C₁₅H₂₁NO₃
MW: 263.33 g/mol

ZX-025154

Methyl 4-((2R,4S)-4-ethoxypiperidin-2-yl)benzoate

CAS: 2408761-26-0
Formula: C₁₅H₂₁NO₃
MW: 263.33 g/mol

ZX-025152

Methyl 4-((2S,4R)-4-ethoxypiperidin-2-yl)benzoate

CAS: 2920219-98-1
Formula: C₁₅H₂₁NO₃
MW: 263.33 g/mol

ZX-025153

Methyl 4-methoxycarbonylbenzoylacetate

CAS: 22027-52-7
Formula: C₁₂H₁₂O₅
MW: 236.22 g/mol

ZX-039287

Tert-Butyl 4-formyl-5-methoxy-7-methyl-1H-indole-1-carboxylate

CAS: 1481631-51-9
Formula: C₁₆H₁₉NO₄
MW: 289.33 g/mol

ZX-045379

Questions

Iptacopan impurities, answered

What Iptacopan reference materials are available?

The catalogue currently lists 10 compounds for Iptacopan, including 1 metabolite or hydroxylated analogue. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.

What documents come with a Iptacopan impurity standard?

A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.

Can Zemixal make a Iptacopan impurity that is not listed?

Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.