Impurity reference standards

Omadacycline impurity standards

For Omadacycline, the Zemixal catalogue holds 12 impurity and reference standards that support release testing, stability programmes and regulatory dossiers. Counted by type, there are 9 metabolites or hydroxylated analogues.

12reference materials

9metabolites

Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions.

By impurity type

Metabolites9Hydroxy, desmethyl and conjugated forms

Counts are based on product names. One compound can fall into more than one type.

All Omadacycline reference materials

1–12 of 12 standards

(4R,4AS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-((neopentylamino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

CAS: 601455-29-2
Formula: C₂₉H₄₀N₄O₇
MW: 556.6 g/mol

ZX-030941

(4S,4AS,12aS)-4,7-Bis(dimethylamino)-3,10,11,12a-tetrahydroxy-9-((neopentylamino)methyl)-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide

CAS: 2272886-35-6
Formula: C₂₉H₃₈N₄O₇
MW: 554.6 g/mol

ZX-030944

(4S,4AS,5aR,12aS)-12-Amino-4,7-bis(dimethylamino)-3,10,12a-trihydroxy-9-((neopentylamino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

CAS: 2272886-39-0
Formula: C₂₉H₄₁N₅O₆
MW: 555.7 g/mol

ZX-030946

(4S,4AS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-7-(methylamino)-9-((neopentylamino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

CAS: 2272886-38-9
Formula: C₂₈H₃₈N₄O₇
MW: 542.6 g/mol

ZX-030942

(4S,4AS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-((1-neopentylureido)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

CAS: 2272886-37-8
Formula: C₃₀H₄₁N₅O₈
MW: 599.7 g/mol

ZX-030943

(4S,4AS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-((methyl(neopentyl)amino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

CAS: 488819-64-3
Formula: C₃₀H₄₂N₄O₇
MW: 570.7 g/mol

ZX-025932

(4S,4AS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-((neopentylamino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,11a,12,12a-decahydrotetracene-2-carboxamide

CAS: 2272886-40-3
Formula: C₂₉H₄₂N₄O₇
MW: 558.7 g/mol

ZX-025934

(4S,4AS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-((neopentylamino)methyl)-4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione

CAS: 2272886-34-5
Formula: C₂₈H₃₉N₃O₆
MW: 513.6 g/mol

ZX-030945

(4S,4AS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-N-(hydroxymethyl)-9-((neopentylamino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

CAS: 1075240-42-4
Formula: C₃₀H₄₂N₄O₈
MW: 586.7 g/mol

ZX-025933

4-Desdimethylamine 4-Oxo Omadacycline

CAS: 885112-31-2
Formula: C₂₇H₃₃N₃O₈
MW: 527.6 g/mol

ZX-025935

Omadacycline

CAS: 389139-89-3
Formula: C₂₉H₄₀N₄O₇
MW: 556.6 g/mol

ZX-025931

Omadacycline Tosylate

CAS: 1075240-43-5
Formula: C₃₆H₄₈N₄O₁₀S
MW: 728.9 g/mol

ZX-030947

Questions

Omadacycline impurities, answered

What Omadacycline reference materials are available?

The catalogue currently lists 12 compounds for Omadacycline, including 9 metabolites or hydroxylated analogues. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.

What documents come with a Omadacycline impurity standard?

A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.

Can Zemixal make a Omadacycline impurity that is not listed?

Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.