Impurity reference standards

Posaconazole impurity standards

Zemixal lists 85 reference materials related to Posaconazole, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 1 isotope-labelled standard, 8 metabolites or hydroxylated analogues and 1 degradation product.

85reference materials

1isotope labelled

8metabolites

1degradants

Parent API

Posaconazole

CAS: 171228-49-2
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol
Code: ZX-006729

Batches are supplied with a certificate of analysis, and the supporting spectra can be sent ahead of a purchase order so your QA team can review them. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions.

By impurity type

Isotope labelled1Deuterated, 13C or 15N internal standards

Metabolites8Hydroxy, desmethyl and conjugated forms

Degradants1N-oxides, dimers, lactones and breakdown products

Counts are based on product names. One compound can fall into more than one type.

All Posaconazole reference materials

1–60 of 85 standards

((2R,3S)-2-(benzyloxy)pentan-3-yl)hydrazine

Formula: C₁₂H₂₀N₂O
MW: 208.3 g/mol

ZX-011785

((2S,3S)-2-(Benzyloxy)pentan-3-yl)hydrazine (2S,3S)-2,3-bis(benzoyloxy)succinate

CAS: 1246365-31-0
Formula: C₃₀H₃₄N₂O₉
MW: 566.6 g/mol

ZX-042373

((2S)-2-(Benzyloxy)pentan-3-yl)hydrazine

CAS: 2306297-05-0
Formula: C₁₂H₂₀N₂O
MW: 208.3 g/mol

ZX-011786

((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

CAS: 159811-30-0
Formula: C₂₁H₂₁F₂N₃O₄S
MW: 449.5 g/mol

ZX-031915

((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

CAS: 149809-42-7
Formula: C₂₁H₂₁F₂N₃O₄S
MW: 449.5 g/mol

ZX-031916

((3S,5R)-5-(2,4-Difluorophenyl)-5-(iodomethyl)tetrahydrofuran-3-yl)methyl Isobutyrate

CAS: 1042398-26-4
Formula: C₁₆H₁₉F₂IO₃
MW: 424.22 g/mol

ZX-031924

(2S)-2-(Benzyloxy)pentan-3-ol

CAS: 1822329-44-1
Formula: C₁₂H₁₈O₂
MW: 194.27 g/mol

ZX-011807

(2S)-2-(Benzyloxy)pentan-3-yl 4-chlorobenzenesulfonate

Formula: C₁₈H₂₁ClO₄S
MW: 368.87 g/mol

ZX-011808

(2S)-2-Hydroxy-1-(1-pyrrolidinyl)-1-propanone

CAS: 122151-38-6
Formula: C₇H₁₃NO₂
MW: 143.18 g/mol

ZX-011809

(S)-2-(Benzyloxy)-1-(pyrrolidin-1-yl)propan-1-one

CAS: 122151-32-0
Formula: C₁₄H₁₉NO₂
MW: 233.31 g/mol

ZX-011853

(S)-2-Benzyloxy-3-pentanone

CAS: 132489-33-9
Formula: C₁₂H₁₆O₂
MW: 192.25 g/mol

ZX-011857

(S)-Lactic Acid Ethyl Ester

CAS: 687-47-8
Formula: C₅H₁₀O₃
MW: 118.13 g/mol

ZX-011863

1-(3-Bromoprop-1-en-2-yl)-2,4-difluorobenzene

CAS: 159276-58-1
Formula: C₉H₇BrF₂
MW: 233.05 g/mol

ZX-036008

1-(4-Hydroxyphenyl)piperazine

CAS: 56621-48-8
Formula: C₁₀H₁₄N₂O
MW: 178.23 g/mol

ZX-034570

1-Bromo-4-phenoxybenzene

CAS: 101-55-3
Formula: C₁₂H₉BrO
MW: 249.1 g/mol

ZX-011913

2-((2S,3S)-2-Hydroxypentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS: 687132-01-0
Formula: C₂₃H₂₉N₅O₃
MW: 423.5 g/mol

ZX-026468

2-(2,4-difluorophenyl)-2-oxoethyl acetate

CAS: 122263-03-0
Formula: C₁₀H₈F₂O₃
MW: 214.16 g/mol

ZX-011964

4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS: 213381-02-3
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-031925

4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS: 2243785-97-7
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-022540

All-(S)-Posaconazole

CAS: 1246391-73-0
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-031917

Desethylene Posaconazole N-Formyl

CAS: 357189-96-9
Formula: C₃₆H₄₀F₂N₈O₅
MW: 702.7 g/mol

ZX-006262

Deshydroxy Posaconazole

CAS: 161532-65-6
Formula: C₃₇H₄₂F₂N₈O₃
MW: 684.8 g/mol

ZX-022539

Deshydroxypentanyl Posaconazole

CAS: 161532-56-5
Formula: C₃₂H₃₂F₂N₈O₃
MW: 614.6 g/mol

ZX-006263

N'-((2R,3R)-2-(Benzyloxy)pentan-3-yl)formohydrazide

CAS: 2173414-68-9
Formula: C₁₃H₂₀N₂O₂
MW: 236.31 g/mol

ZX-031928

N'-((2R,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide

CAS: 2243785-81-9
Formula: C₁₃H₂₀N₂O₂
MW: 236.31 g/mol

ZX-012634

N'-((2R,3S)-2-(benzyloxy)pentan-3-yl)formohydrazide oxalate

Formula: C₁₃H₂₀N₂O₂.C₂H₂O₄
MW: 326.34 g/mol

ZX-012635

N'-((2S)-2-(benzyloxy)pentan-3-yl)formohydrazide (Racemic Mixture)

Formula: C₁₃H₂₀N₂O₂
MW: 236.31 g/mol

ZX-012636

O-Benzyl Posaconazole

CAS: 170985-86-1
Formula: C₄₄H₄₈F₂N₈O₄
MW: 790.9 g/mol

ZX-026467

Posacanzole Intermediate B

CAS: 74853-08-0
Formula: C₁₆H₁₉N₃O
MW: 269.34 g/mol

ZX-012786

Posaconazole

CAS: 171228-49-2
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-006729

Posaconazole 2R,3R Diastereoisomer

CAS: 170985-61-2
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-005153

Posaconazole 2R,3S Diastereoisomer

CAS: 171228-51-6
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-005154

Posaconazole 3-Oxo Impurity

CAS: 357189-94-7
Formula: C₃₇H₄₀F₂N₈O₅
MW: 714.8 g/mol

ZX-005155

Posaconazole 4-Oxido Impurity

CAS: 1902954-05-5
Formula: C₃₇H₄₂F₂N₈O₅
MW: 716.8 g/mol

ZX-005156

Posaconazole BHB R,R-Isomer

CAS: 2243786-01-6
Formula: C₃₀H₃₅N₅O₃
MW: 513.6 g/mol

ZX-005157

Posaconazole BHB R,S-Isomer

CAS: 2243786-00-5
Formula: C₃₀H₃₅N₅O₃
MW: 513.6 g/mol

ZX-005158

Posaconazole BHB RS and RR-Isomer (Mixture)

CAS: 2243786-00-5
Formula: C₃₀H₃₅N₅O₃
MW: 513.6 g/mol

ZX-005159

Posaconazole BHB S,R-Isomer

CAS: 2243786-02-7
Formula: C₃₀H₃₅N₅O₃
MW: 513.6 g/mol

ZX-005160

Posaconazole BHB S,S-Isomer

CAS: 184177-83-1
Formula: C₃₀H₃₅N₅O₃
MW: 513.6 g/mol

ZX-005161

Posaconazole CPD-4

CAS: 184378-04-9
Formula: C₃₀H₃₂F₂N₆O₂
MW: 546.6 g/mol

ZX-012787

Posaconazole CPD-5

CAS: 161532-54-3
Formula: C₃₇H₃₆F₂N₆O₄
MW: 666.7 g/mol

ZX-012788

Posaconazole CPD-6

Formula: C₄₈H₅₈F₂N₈O₆
MW: 881.02 g/mol

ZX-012789

Posaconazole Desethylene Diformyl Impurity

CAS: 357189-95-8
Formula: C₃₇H₄₀F₂N₈O₆
MW: 730.8 g/mol

ZX-006330

Posaconazole Desformyl Impurity

CAS: 183871-34-3
Formula: C₁₂H₂₀N₂O
MW: 208.3 g/mol

ZX-006331

Posaconazole Desformyl Impurity(Oxalic Acid Salt)

CAS: 2356140-65-1
Formula: C₁₄H₂₂N₂O₅
MW: 298.33 g/mol

ZX-006332

Posaconazole Diastereoisomer (S,R,S,S)

CAS: 2243785-96-6
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-026469

Posaconazole Diastereoisomer 2

CAS: 213381-05-6
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-031920

Posaconazole Diastereoisomer 3 (S,R,R,R)

CAS: 1229428-89-0
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-031919

Posaconazole Diastereoisomer 4 (S,S,R,R)

CAS: 2243785-98-8
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-031923

Posaconazole Diastereoisomer 5

CAS: 1229428-90-3
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-031921

Posaconazole Diastereoisomer 7 (R,S,R,S)

CAS: 213381-04-5
Formula: C₃₇H₄₂F₂N₈O₄
MW: 700.8 g/mol

ZX-031922

Posaconazole Diastereoisomer Related Compound 2

CAS: 166583-12-6
Formula: C₂₁H₂₁F₂N₃O₄S
MW: 449.5 g/mol

ZX-005162

Posaconazole Diastereoisomer Related Compound 8

CAS: 149809-43-8
Formula: C₂₁H₂₁F₂N₃O₄S
MW: 449.5 g/mol

ZX-005163

Posaconazole Formamide Impurity

CAS: 357189-97-0
Formula: C₂₁H₂₀F₂N₄O₃
MW: 414.4 g/mol

ZX-005164

Posaconazole Formate

CAS: 2069239-68-3
Formula: C₃₈H₄₂F₂N₈O₅
MW: 728.8 g/mol

ZX-012790

Posaconazole Formyl Impurity (R-isomer)Oxalic Acid Salt -Stage-1

CAS: 151670-13-2
Formula: C₇H₁₃NO₂
MW: 143.18 g/mol

ZX-005165

Posaconazole Formyl Impurity (R-isomer)Oxalic Acid Salt -Stage-2

CAS: 2184724-37-4
Formula: C₁₄H₁₉NO₂
MW: 233.31 g/mol

ZX-005166

Posaconazole Formyl Impurity (R-isomer)Oxalic Acid Salt-Stage-3

CAS: 132489-34-0
Formula: C₁₂H₁₆O₂
MW: 192.25 g/mol

ZX-005167

Posaconazole Formyl Semicarbazide Analog

CAS: 1350560-57-4
Formula: C₃₇H₄₄F₂N₈O₅
MW: 718.8 g/mol

ZX-012791

Posaconazole Hydroxy Carbamate Impurity

CAS: 184177-81-9
Formula: C₂₃H₂₃N₃O₃
MW: 389.4 g/mol

ZX-005168

Questions

Posaconazole impurities, answered

How many Posaconazole impurity standards does Zemixal list?

The catalogue currently lists 85 compounds for Posaconazole, including 1 isotope-labelled standard, 8 metabolites or hydroxylated analogues and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.

What documents come with a Posaconazole impurity standard?

A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.

Can Zemixal make a Posaconazole impurity that is not listed?

Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.

Are isotope-labelled Posaconazole standards available?

Yes. 1 stable-isotope labelled compound is listed, suitable as internal standards for LC-MS bioanalysis and trace impurity quantitation.