(E)-Ethyl (2-cyano-2-(2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)hydrazono)acetyl)carbamate
- CAS
- 920509-33-7
- Formula
- C19H18Cl2N6O5
- MW
- 481.3 g/mol
ZX-022641
Impurity reference standards
Resmetirom impurity standards
For Resmetirom, the Zemixal catalogue holds 18 impurity and reference standards that support release testing, stability programmes and regulatory dossiers. Counted by type, there are 1 metabolite or hydroxylated analogue.
18reference materials
1metabolites
Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions.
By impurity type
Metabolites1Hydroxy, desmethyl and conjugated forms
Counts are based on product names. One compound can fall into more than one type.
All Resmetirom reference materials
1–18 of 18 standards
2-(3-Chloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile
- CAS
- 2639977-02-7
- Formula
- C17H13ClN6O4
- MW
- 400.8 g/mol
ZX-032159
2-(3,5-Dichloro-4-((5-(1-hydroxypropan-2-yl)-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile
- CAS
- 2222607-69-2
- Formula
- C17H12Cl2N6O5
- MW
- 451.2 g/mol
ZX-032160
2-(3,5-Dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-1,2,4-triazine-3,5(2H,4H)-dione
- CAS
- 920509-34-8
- Formula
- C16H13Cl2N5O4
- MW
- 410.2 g/mol
ZX-020385
2-(3,5-Dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide
- CAS
- 2542029-02-5
- Formula
- C17H14Cl2N6O5
- MW
- 453.2 g/mol
ZX-020382
2-(3,5-Dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxylic Acid
- CAS
- 920509-35-9
- Formula
- C17H13Cl2N5O6
- MW
- 454.2 g/mol
ZX-020384
2-[3,5-Dichloro-4-[[6-chloro-5-(1-methylethyl)-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triazine-6-carbonitrile
- CAS
- 2403721-20-8
- Formula
- C17H11Cl3N6O3
- MW
- 453.7 g/mol
ZX-020383
2-Amino-N-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-2-oxoacetohydrazonoyl cyanide
- CAS
- 2987937-25-5
- Formula
- C16H14Cl2N6O3
- MW
- 409.2 g/mol
ZX-026689
3,5-Dichloro-4-((6-chloropyridazin-3-yl)oxy)aniline
- CAS
- 1581304-46-2
- Formula
- C10H6Cl3N3O
- MW
- 290.5 g/mol
ZX-022643
6-(4-Amino-2,6-dichlorophenoxy)-5-isopropylpyridazin-3(2H)-one
- CAS
- 2768217-12-3
- Formula
- C13H13Cl2N3O2
- MW
- 314.16 g/mol
ZX-022642
N-(3,5-Dichloro-4-((6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)benzamide
- CAS
- 1581304-48-4
- Formula
- C17H11Cl2N3O3
- MW
- 376.2 g/mol
ZX-042438
Questions
Resmetirom impurities, answered
What Resmetirom reference materials are available?
The catalogue currently lists 18 compounds for Resmetirom, including 1 metabolite or hydroxylated analogue. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Resmetirom impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Resmetirom impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.