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Impurity reference standards

Thiamine impurity standards

This page brings together 28 Thiamine related compounds that analytical teams use to identify, quantify and control impurities in the active ingredient and the finished dosage form. The range includes 6 pharmacopoeial impurities and 3 metabolites or hydroxylated analogues.

28reference materials
6pharmacopoeial
3metabolites
Thiamine structure
Parent API

Thiamine

CAS
70-16-6
Formula
C12H17N4OS+
MW
265.36 g/mol
Code
ZX-006856

Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. Typical uses are method development and validation, relative response factor work, forced degradation studies and the impurity sections of ANDA, DMF or CEP filings.

By impurity type

Pharmacopoeial6EP, USP, BP or JP named impurities
Metabolites3Hydroxy, desmethyl and conjugated forms

Counts are based on product names. One compound can fall into more than one type.

All Thiamine reference materials

1–28 of 28 standards
Questions

Thiamine impurities, answered

What Thiamine reference materials are available?
The catalogue currently lists 28 compounds for Thiamine, including 6 pharmacopoeial impurities and 3 metabolites or hydroxylated analogues. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Thiamine impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Thiamine impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
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