Impurity reference standards
Ticagrelor impurity standards
Zemixal lists 66 reference materials related to Ticagrelor, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 6 pharmacopoeial impurities and 4 metabolites or hydroxylated analogues.
66reference materials
6pharmacopoeial
4metabolites
Every standard comes with a certificate of analysis. Structure confirmation data, typically NMR, MS and chromatographic purity, is available on request. Laboratories use them to validate related-substance methods, set specification limits under ICH Q3A and Q3B, and identify unknown peaks in stability samples.
By impurity type
Pharmacopoeial6EP, USP, BP or JP named impurities
Metabolites4Hydroxy, desmethyl and conjugated forms
Counts are based on product names. One compound can fall into more than one type.
All Ticagrelor reference materials
1–60 of 66 standards
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide
- CAS
- 1006376-62-0
- Formula
- C10H9F2NO
- MW
- 197.18 g/mol
ZX-022909
(1R,2S)-2-(2,3-Difluorophenyl)cyclopropan-1-amine
- CAS
- 1427524-53-5
- Formula
- C9H9F2N
- MW
- 169.17 g/mol
ZX-032655
(1R,2S)-2-(3-Fluorophenyl)cyclopropan-1-amine hydrochloride
- CAS
- 1643378-58-8
- Formula
- C9H11ClFN
- MW
- 187.64 g/mol
ZX-036295
(1R,2S)-Rel-2-(3,4-Difluorophenyl) cyclopropanamine hydrochloride
- CAS
- 1156491-10-9
- Formula
- C9H10ClF2N
- MW
- 205.63 g/mol
ZX-032653
(1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- CAS
- 2056269-94-2
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol
ZX-027255
(1S,2S,3R,5S)-3-(7-Hydroxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
- CAS
- 1445580-43-7
- Formula
- C14H21N5O5S
- MW
- 371.41 g/mol
ZX-027253
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(2,3-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
- CAS
- 1643378-48-6
- Formula
- C23H28F2N6O4S
- MW
- 522.6 g/mol
ZX-027258
(3AR,4R,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol
- CAS
- 2715109-35-4
- Formula
- C8H15NO3
- MW
- 173.21 g/mol
ZX-027272
(3AR,4S,6S,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol
- CAS
- 2376278-80-5
- Formula
- C8H15NO3
- MW
- 173.21 g/mol
ZX-027271
2-(((3AR,4S,6R,6aS)-6-(7-Amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol
- CAS
- 1858267-99-8
- Formula
- C17H26N6O4S
- MW
- 410.5 g/mol
ZX-027273
2-(((3AR,4S,6S,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
- CAS
- 2376278-69-0
- Formula
- C10H19NO4
- MW
- 217.26 g/mol
ZX-027270
2-(2-(Benzyloxy)ethoxy)ethyl,4-methylbenzenesulfonate
- CAS
- 98627-22-6
- Formula
- C18H22O5S
- MW
- 350.4 g/mol
ZX-042588
2-[[(3AS,4R,6S,6aR)-4-Aminotetrahydro-2,2-dimethyl-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol Oxalate
- CAS
- 1402150-30-4
- Formula
- C12H21NO8
- MW
- 307.3 g/mol
ZX-042590
4,6-Dichloro-2-propylthiopyrimidine-5-amine hydrochloride
- CAS
- 2497548-30-6
- Formula
- C7H9Cl2N3S.ClH
- MW
- 274.59 g/mol
ZX-012106
5-Amino-6-chloro-2-(propylthio)pyrimidin-4-ol
- CAS
- 2512210-21-6
- Formula
- C7H10ClN3OS
- MW
- 219.69 g/mol
ZX-036289
6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone
- CAS
- 1548397-10-9
- Formula
- C7H8ClN3O3S
- MW
- 249.68 g/mol
ZX-027267
Ethyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetat
- CAS
- 1265919-24-1
- Formula
- C12H21NO5
- MW
- 259.3 g/mol
ZX-032654
Ticagrelor Impurity L (Mixture of Diastereomers)
- CAS
- 1644461-85-7
- Formula
- C23H28F2N6O5S
- MW
- 538.6 g/mol
ZX-027250
Ticagrelor Related Compound 38 ((2R,3R)-Tartaric acid)
- CAS
- 2459945-85-6
- Formula
- C14H25NO10
- MW
- 367.35 g/mol
ZX-005430
Questions
Ticagrelor impurities, answered
How many Ticagrelor impurity standards does Zemixal list?
The catalogue currently lists 66 compounds for Ticagrelor, including 6 pharmacopoeial impurities and 4 metabolites or hydroxylated analogues. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Ticagrelor impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Ticagrelor impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.