(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
- CAS
- 1062580-52-2
- Formula
- C14H24Cl2N2
- MW
- 291.3 g/mol
ZX-011813
Impurity reference standards
Tofacitinib impurity standards
Zemixal lists 44 reference materials related to Tofacitinib, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 1 metabolite or hydroxylated analogue and 1 degradation product.
44reference materials
1metabolites
1degradants
Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions.
By impurity type
Metabolites1Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products
Counts are based on product names. One compound can fall into more than one type.
All Tofacitinib reference materials
1–44 of 44 standards
(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
- CAS
- 1821769-41-8
- Formula
- C14H24Cl2N2
- MW
- 291.3 g/mol
ZX-027313
(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
- CAS
- 1354486-07-9
- Formula
- C14H24Cl2N2
- MW
- 291.3 g/mol
ZX-011817
3-((3R,4R)-3-((6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
- CAS
- 1809002-40-1
- Formula
- C22H30N6O8
- MW
- 506.5 g/mol
ZX-027308
3-((3R,4R)-3-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
- CAS
- 1527525-58-1
- Formula
- C15H18N6O
- MW
- 298.34 g/mol
ZX-027320
3-((3R,4R)-4-Methyl-3-(methyl(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
- CAS
- 2101951-20-4
- Formula
- C16H20N6O2
- MW
- 328.37 g/mol
ZX-027316
3-((3R,4R)-4-Methyl-3-(methyl(6-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
- CAS
- 1640971-51-2
- Formula
- C16H20N6O2
- MW
- 328.37 g/mol
ZX-027318
3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid
- CAS
- 2328165-36-0
- Formula
- C16H21N5O3
- MW
- 331.37 g/mol
ZX-027314
4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidine hydrochloride
- CAS
- 1243346-92-0
- Formula
- C6H5Cl2N3
- MW
- 190.03 g/mol
ZX-012150
4-Chloro-1H-pyrrolo[2,3-d]pyrimidine potassium salt
- CAS
- 145594-16-7
- Formula
- C6H4ClN3.K
- MW
- 192.67 g/mol
ZX-012151
4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidine Sodium Salt
- CAS
- 443642-59-9
- Formula
- C6H4ClN3.Na
- MW
- 176.56 g/mol
ZX-012152
Ethyl 4-cyano-3-imino-5-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentanoate
- CAS
- 2102039-99-4
- Formula
- C21H27N7O3
- MW
- 425.5 g/mol
ZX-027319
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- CAS
- 923036-30-0
- Formula
- C27H31N5O2S
- MW
- 489.6 g/mol
ZX-027311
N-((3R,4R)-1,4-Dimethylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- CAS
- 2227197-38-6
- Formula
- C14H21N5
- MW
- 259.35 g/mol
ZX-027317
N-Methyl-N-(3R,4R)-1-cyanoacetyl-4-methylpiperidin-3-yl-2-chloro-7-deazapurine-6-amine
- CAS
- 1616761-00-2
- Formula
- C16H19ClN6O
- MW
- 346.81 g/mol
ZX-027315
Questions
Tofacitinib impurities, answered
How many Tofacitinib impurity standards does Zemixal list?
The catalogue currently lists 44 compounds for Tofacitinib, including 1 metabolite or hydroxylated analogue and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Tofacitinib impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Tofacitinib impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.