Impurity reference standards

Zopiclone impurity standards

For Zopiclone, the Zemixal catalogue holds 14 impurity and reference standards that support release testing, stability programmes and regulatory dossiers. Counted by type, there are 3 pharmacopoeial impurities, 2 isotope-labelled standards and 1 metabolite or hydroxylated analogue.

14reference materials

3pharmacopoeial

2isotope labelled

1metabolites

Parent API

Zopiclone

CAS: 43200-80-2
Formula: C₁₇H₁₇ClN₆O₃
MW: 388.8 g/mol
Code: ZX-006922

Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. Laboratories use them to validate related-substance methods, set specification limits under ICH Q3A and Q3B, and identify unknown peaks in stability samples.

By impurity type

Pharmacopoeial3EP, USP, BP or JP named impurities

Isotope labelled2Deuterated, 13C or 15N internal standards

Metabolites1Hydroxy, desmethyl and conjugated forms

Counts are based on product names. One compound can fall into more than one type.

All Zopiclone reference materials

1–14 of 14 standards

(R)-Zopiclone

CAS: 138680-08-7
Formula: C₁₇H₁₇ClN₆O₃
MW: 388.8 g/mol

ZX-004268

2-Amino-5-chloropyridine

CAS: 1072-98-6
Formula: C₅H₅ClN₂
MW: 128.56 g/mol

ZX-011986

2-Amino-5-Chloropyridine Hydrochloride

CAS: 94770-74-8
Formula: C₅H₆Cl₂N₂
MW: 165.02 g/mol

ZX-011987

3-(5-Chloropyridine-2-carbamoyl)-2- pyrazinecarboxylic Acid

CAS: 43200-83-5
Formula: C₁₁H₇ClN₄O₃
MW: 278.65 g/mol

ZX-043028

N-(5-Chloro-2-pyridinyl)-2-pyrazinecarboxamide

CAS: 349125-10-6
Formula: C₁₀H₇ClN₄O
MW: 234.64 g/mol

ZX-043029

N-Desmethyl Zopiclone

CAS: 59878-63-6
Formula: C₁₆H₁₅ClN₆O₃
MW: 374.78 g/mol

ZX-036520

Piperazine-1-carbonyl chloride

CAS: 69433-07-4
Formula: C₅H₉ClN₂O
MW: 148.59 g/mol

ZX-031616

Zopiclone

CAS: 43200-80-2
Formula: C₁₇H₁₇ClN₆O₃
MW: 388.8 g/mol

ZX-006922

Zopiclone EP Impurity A

CAS: 43200-96-0
Formula: C₁₇H₁₇ClN₆O₄
MW: 404.8 g/mol

ZX-006076

Zopiclone EP Impurity B

CAS: 43200-81-3
Formula: C₁₁H₇ClN₄O₂
MW: 262.65 g/mol

ZX-006077

Zopiclone EP impurity C

CAS: 148891-53-6
Formula: C₁₁H₇ClN₄O
MW: 246.65 g/mol

ZX-006078

Zopiclone Impurity 2

CAS: 43200-82-4
Formula: C₁₁H₅ClN₄O₂
MW: 260.63 g/mol

ZX-005543

Zopiclone-D4

CAS: 1435933-78-0
Formula: C₁₇H₁₇ClN₆O₃
MW: 392.8 g/mol

ZX-044702

Zopiclone-d8

CAS: 1215518-83-4
Formula: C₁₇H₁₇ClN₆O₃
MW: 396.9 g/mol

ZX-043194

Questions

Zopiclone impurities, answered

What Zopiclone reference materials are available?

The catalogue currently lists 14 compounds for Zopiclone, including 3 pharmacopoeial impurities, 2 isotope-labelled standards and 1 metabolite or hydroxylated analogue. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.

What documents come with a Zopiclone impurity standard?

A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.

Can Zemixal make a Zopiclone impurity that is not listed?

Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.

Are isotope-labelled Zopiclone standards available?

Yes. 2 stable-isotope labelled compounds are listed, suitable as internal standards for LC-MS bioanalysis and trace impurity quantitation.