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Pharmacopeial Impurities (EP / USP / BP)

Donepezil EP Impurity F

Reference StandardAvailable on request

Order Donepezil EP Impurity F (CAS 145546-80-1) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery. Packs from 10 mg.

Pack sizes
Donepezil EP Impurity F chemical structure
CAS number145546-80-1
FormulaC24H27NO3
Molar mass377.5 g/mol
Physical formSolid
HS code38229090
InChIKeyLPMOTUSFDTTWJL-UDWIEESQSA-N
IUPAC name(2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-3H-inden-1-one

About Donepezil EP Impurity F

Donepezil EP Impurity F belongs to the Donepezil reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 145546-80-1, formula C24H27NO3 and molar mass 377.5 g/mol. It is handled as a solid.

Where it is used

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

Classified under GHS with signal word Danger and hazard statements H300. Read the SDS before first use.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Donepezil

See every impurity, metabolite and related compound we list for this API.

Donepezil standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Grade guides

Specifications and identifiers

Specifications of Donepezil EP Impurity F
Product nameDonepezil EP Impurity F
Catalogue numberZX-024340
CAS number145546-80-1
IUPAC name(2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-3H-inden-1-one
Molecular formulaC24H27NO3
Molar mass377.5 g/mol
Exact mass377.1991
GradeReference Standard
Physical formSolid
XLogP34.2
H-bond donors / acceptors0 / 4
Topological polar surface area38.8 Ų
HS code38229090
InChIKeyLPMOTUSFDTTWJL-UDWIEESQSA-N
SMILESCOC1=C(C=C2C(=C1)C/C(=C\C3CCN(CC3)CC4=CC=CC=C4)/C2=O)OC
PubChem CID10762160
Synonyms(2E)-Dehydrodonepezil, Donepezil - Impurity F, Donepezil Related Compound A, (E)-2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxyindan-1-one, 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxyindan-1-one, (E)-, 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one, 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine, (E)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one, (2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one, 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methylene]-, (2~{E})-5,6-dimethoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methylidene]-3~{H}-inden-1-one, 2-[(1-Benzyl-4-piperidyl)methylene]-5,6-dimethoxy-1-indanone

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity

Signal word Danger

  • H300Fatal if swallowed

Precautionary statements P264, P270, P301 + P316, P321, P330, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Donepezil EP Impurity F
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Donepezil EP Impurity F

Which CAS number identifies Donepezil EP Impurity F?
Donepezil EP Impurity F is registered under CAS 145546-80-1. You may also see it listed as (2E)-Dehydrodonepezil, Donepezil - Impurity F, Donepezil Related Compound A. Our catalogue number for this item is ZX-024340.
What are the formula and molar mass of Donepezil EP Impurity F?
For Donepezil EP Impurity F, its formula is C24H27NO3 and its molar mass is 377.5 g/mol. The systematic (IUPAC) name is (2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-3H-inden-1-one. InChIKey LPMOTUSFDTTWJL-UDWIEESQSA-N lets you match it in any structure database.
How is Donepezil EP Impurity F used in pharmaceutical QC?
Donepezil EP Impurity F is a characterised reference material linked to Donepezil. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Donepezil EP Impurity F?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Donepezil EP Impurity F?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Donepezil EP Impurity F to my country?
Yes. Because Donepezil EP Impurity F is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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