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Pharmacopeial Impurities (EP / USP / BP)

Pemetrexed EP Impurity E

Reference StandardAvailable on request

Order Pemetrexed EP Impurity E (CAS 182009-04-7) online at Zemixal: C20H21N5O6, COA and SDS with every lot, worldwide shipping.

Pack sizes
Pemetrexed EP Impurity E chemical structure
CAS number182009-04-7
FormulaC20H21N5O6
Molar mass427.4 g/mol
Physical formSolid
HS code38229090
InChIKeyWBXPDJSOTKVWSJ-CYBMUJFWSA-N
IUPAC name(2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

About Pemetrexed EP Impurity E

Zemixal lists Pemetrexed EP Impurity E for laboratories that identify, quantify or control Pemetrexed and its related substances. For your records (Reference Standard), the material is defined by CAS 182009-04-7, formula C20H21N5O6 and molar mass 427.4 g/mol. It is handled as a solid.

Where it is used

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Handling and storage

Classified under GHS with signal word Danger and hazard statements H315, H319, H341 and H360. Read the SDS before first use.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Pemetrexed

See every impurity, metabolite and related compound we list for this API.

Pemetrexed standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Pemetrexed EP Impurity E
Product namePemetrexed EP Impurity E
Catalogue numberZX-005882
CAS number182009-04-7
Other CAS numbers937370-10-0
IUPAC name(2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
Molecular formulaC20H21N5O6
Molar mass427.4 g/mol
Exact mass427.1492
GradeReference Standard
Physical formSolid
XLogP30.2
H-bond donors / acceptors6 / 7
Topological polar surface area187 Ų
HS code38229090
InChIKeyWBXPDJSOTKVWSJ-CYBMUJFWSA-N
SMILESC1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@H](CCC(=O)O)C(=O)O
PubChem CID135565230
SynonymsD-Pemetrexed, (D)-Pemetrexed, Pemetrexed R-Isomer, (R)-Pemetrexed, Pemetrexed, (R)-, Pemetrexed (R) enantiomer, D-Pemetrexed Hydrate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H341Suspected of causing genetic defects
  • H360May damage fertility or the unborn child
  • H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Pemetrexed EP Impurity E
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Pemetrexed EP Impurity E

Which CAS number identifies Pemetrexed EP Impurity E?
Pemetrexed EP Impurity E is registered under CAS 182009-04-7. You may also see it listed as D-Pemetrexed, (D)-Pemetrexed, Pemetrexed R-Isomer. Our catalogue number for this item is ZX-005882.
What are the formula and molar mass of Pemetrexed EP Impurity E?
For Pemetrexed EP Impurity E, its formula is C20H21N5O6 and its molar mass is 427.4 g/mol. The systematic (IUPAC) name is (2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid. InChIKey WBXPDJSOTKVWSJ-CYBMUJFWSA-N lets you match it in any structure database.
How is Pemetrexed EP Impurity E used in pharmaceutical QC?
Pemetrexed EP Impurity E is a characterised reference material linked to Pemetrexed. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Pemetrexed EP Impurity E?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Pemetrexed EP Impurity E?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Pemetrexed EP Impurity E to my country?
Yes. Because Pemetrexed EP Impurity E is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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