(R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
- CAS
- 402855-07-6
- Formula
- C18H14ClFN4O4
- MW
- 404.8 g/mol
ZX-027781
API Impurities
(S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
Reference StandardAvailable on request
Buy (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine (CAS 2044709-72-8) from Zemixal…
CAS number2044709-72-8
FormulaC18H16F2N4O2
Molar mass358.3 g/mol
Physical formSolid
HS code38229090
InChIKeyXGUCTFIMQFLKRU-NSHDSACASA-N
IUPAC name4-N-(3,4-difluorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine
About (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
Zemixal lists (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine for laboratories that identify, quantify or control Afatinib and its related substances. Key data (Reference Standard): CAS 2044709-72-8, formula C18H16F2N4O2 and molar mass 358.3 g/mol. It is handled as a solid.
Where it is used
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.
Reference standards for Afatinib
See every impurity, metabolite and related compound we list for this API.
Afatinib standardsTypical uses
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Applications
Specifications and identifiers
| Product name | (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine |
|---|---|
| Catalogue number | ZX-027782 |
| CAS number | 2044709-72-8 |
| IUPAC name | 4-N-(3,4-difluorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine |
| Molecular formula | C18H16F2N4O2 |
| Molar mass | 358.3 g/mol |
| Exact mass | 358.1241 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 3 |
| H-bond donors / acceptors | 2 / 8 |
| Topological polar surface area | 82.3 Ų |
| HS code | 38229090 |
| InChIKey | XGUCTFIMQFLKRU-NSHDSACASA-N |
| SMILES | C1COC[C@H]1OC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=C(C=C4)F)F)N |
| PubChem CID | 127255549 |
| Synonyms | N4-(3,4-difluorophenyl)-7-[(3S)-oxolan-3-yloxy]quinazoline-4,6-diamine |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
Which CAS number identifies (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
(S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine is registered under CAS 2044709-72-8. You may also see it listed as N4-(3,4-difluorophenyl)-7-[(3S)-oxolan-3-yloxy]quinazoline-4,6-diamine. Our catalogue number for this item is ZX-027782.
What are the formula and molar mass of (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
For (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine, its formula is C18H16F2N4O2 and its molar mass is 358.3 g/mol. The systematic (IUPAC) name is 4-N-(3,4-difluorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine. InChIKey XGUCTFIMQFLKRU-NSHDSACASA-N lets you match it in any structure database.
How is (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine used in pharmaceutical QC?
(S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine to my country?
Yes. (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.
More Afatinib standards
More in API Impurities
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
- CAS
- 179552-74-0
- Formula
- C15H10ClFN4O3
- MW
- 348.71 g/mol
ZX-027678
(S,E)-4-(Dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
- CAS
- 2413212-25-4
- Formula
- C24H26FN5O3
- MW
- 451.5 g/mol
ZX-027677
(S)-N4-(4-Fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
- CAS
- 2413212-07-2
- Formula
- C18H17FN4O2
- MW
- 340.4 g/mol
ZX-027676
N-(4-Chloro-3-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
- CAS
- 2475095-50-0
- Formula
- C14H7ClF2N4O2
- MW
- 336.68 g/mol
ZX-023165
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