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Pharmacopeial Impurities (EP / USP / BP)

Naloxone EP Impurity E

Reference StandardAvailable on request

Naloxone EP Impurity E (CAS 211738-08-8) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery. Packs from 10 mg.

Pack sizes
Naloxone EP Impurity E chemical structure
CAS number211738-08-8
FormulaC38H40N2O8
Molar mass652.7 g/mol
Physical formSolid
HS code38229090
InChIKeyVZXBORUALALXQH-ZQUSMLRHSA-N

About Naloxone EP Impurity E

Naloxone EP Impurity E is supplied by Zemixal as a characterised reference material for Naloxon analysis. For your records (Reference Standard), the material is defined by CAS 211738-08-8, formula C38H40N2O8 and molar mass 652.7 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Safe handling

It carries the GHS signal word Danger (H302, H312, H317 and H332), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Naloxon

See every impurity, metabolite and related compound we list for this API.

Naloxon standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Naloxone EP Impurity E
Product nameNaloxone EP Impurity E
Catalogue numberZX-036490
CAS number211738-08-8
IUPAC name(4R,4aS,7aR,12bS)-10-[(4R,4aS,7aR,12bS)-4a,9-dihydroxy-7-oxo-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-10-yl]-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formulaC38H40N2O8
Molar mass652.7 g/mol
Exact mass652.2785
GradeReference Standard
Physical formSolid
XLogP32.6
H-bond donors / acceptors4 / 10
Topological polar surface area140 Ų
HS code38229090
InChIKeyVZXBORUALALXQH-ZQUSMLRHSA-N
SMILESC=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=CC(=C(C(=C35)O4)O)C6=C(C7=C8C(=C6)C[C@@H]9[C@]1([C@]8(CCN9CC=C)[C@@H](O7)C(=O)CC1)O)O)O
PubChem CID129011921
SynonymsNaloxone Hydrochloride EP Impurity E, Naloxone Hydrochloride - Impurity E, 2,2'-Bisnaloxone, Naloxone hydrochloride dihydrate impurity E

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H317May cause an allergic skin reaction
  • H332Harmful if inhaled
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Naloxone EP Impurity E
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Naloxone EP Impurity E

Which CAS number identifies Naloxone EP Impurity E?
Naloxone EP Impurity E is registered under CAS 211738-08-8. You may also see it listed as Naloxone Hydrochloride EP Impurity E, Naloxone Hydrochloride - Impurity E, 2,2'-Bisnaloxone. Our catalogue number for this item is ZX-036490.
What are the formula and molar mass of Naloxone EP Impurity E?
For Naloxone EP Impurity E, its formula is C38H40N2O8 and its molar mass is 652.7 g/mol. InChIKey VZXBORUALALXQH-ZQUSMLRHSA-N lets you match it in any structure database.
How is Naloxone EP Impurity E used in pharmaceutical QC?
Naloxone EP Impurity E is a characterised reference material linked to Naloxon. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Naloxone EP Impurity E?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Naloxone EP Impurity E?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Naloxone EP Impurity E to my country?
Yes. Because Naloxone EP Impurity E is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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