2,4,5-Trifluorophenylacetonitrile

Name: 2,4,5-Trifluorophenylacetonitrile
Brand: Zemixal
SKU: ZX-031274

Reference StandardAvailable on request

Order 2,4,5-Trifluorophenylacetonitrile (CAS 220141-74-2) online at Zemixal. Request a quote with price, lead time and documents.

Pack sizes

2,4,5-Trifluorophenylacetonitrile chemical structure

CAS number220141-74-2

FormulaC₈H₄F₃N

Molar mass171.12 g/mol

Physical formSolid

HS code38229090

InChIKeyJTYBTJVFXUKNKW-UHFFFAOYSA-N

IUPAC name2-(2,4,5-trifluorophenyl)acetonitrile

About 2,4,5-Trifluorophenylacetonitrile

Zemixal lists 2,4,5-Trifluorophenylacetonitrile for laboratories that identify, quantify or control Sitagliptin and its related substances. Identity at a glance (Reference Standard): CAS 220141-74-2, formula C8H4F3N and molar mass 171.12 g/mol. It is handled as a solid.

Use cases we see most often

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Safe handling

Classified under GHS with signal word Danger and hazard statements H301, H302, H311 and H312. Read the SDS before first use.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Sitagliptin

See every impurity, metabolite and related compound we list for this API.

Sitagliptin standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of 2,4,5-Trifluorophenylacetonitrile
Product name	2,4,5-Trifluorophenylacetonitrile
Catalogue number	ZX-031274
CAS number	220141-74-2
IUPAC name	2-(2,4,5-trifluorophenyl)acetonitrile
Molecular formula	C₈H₄F₃N
Molar mass	171.12 g/mol
Exact mass	171.0296
Grade	Reference Standard
Physical form	Solid
XLogP3	1.9
H-bond donors / acceptors	0 / 4
Topological polar surface area	23.8 Å²
HS code	38229090
InChIKey	JTYBTJVFXUKNKW-UHFFFAOYSA-N
SMILES	C1=C(C(=CC(=C1F)F)F)CC#N
PubChem CID	2777957
Synonyms	2,4,5-Trifluorobenzyl Cyanide, 2-(2,4,5-trifluorophenyl)ethanenitrile, 2,4,5-trifluorobenzylcyanide, 2,4,5-Trifluorobenzeneacetonitrile

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Acute toxicity

Irritant or harmful

Signal word Danger

H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H330Fatal if inhaled
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements P260, P261, P262, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P317, P319, P320, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 2,4,5-Trifluorophenylacetonitrile
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 2,4,5-Trifluorophenylacetonitrile

Which CAS number identifies 2,4,5-Trifluorophenylacetonitrile?

2,4,5-Trifluorophenylacetonitrile is registered under CAS 220141-74-2. You may also see it listed as 2,4,5-Trifluorobenzyl Cyanide, 2-(2,4,5-trifluorophenyl)ethanenitrile, 2,4,5-trifluorobenzylcyanide. Our catalogue number for this item is ZX-031274.

What are the formula and molar mass of 2,4,5-Trifluorophenylacetonitrile?

For 2,4,5-Trifluorophenylacetonitrile, its formula is C8H4F3N and its molar mass is 171.12 g/mol. The systematic (IUPAC) name is 2-(2,4,5-trifluorophenyl)acetonitrile. InChIKey JTYBTJVFXUKNKW-UHFFFAOYSA-N lets you match it in any structure database.

How is 2,4,5-Trifluorophenylacetonitrile used in pharmaceutical QC?

2,4,5-Trifluorophenylacetonitrile is a characterised reference material linked to Sitagliptin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for 2,4,5-Trifluorophenylacetonitrile?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with 2,4,5-Trifluorophenylacetonitrile?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship 2,4,5-Trifluorophenylacetonitrile to my country?

Yes. Because 2,4,5-Trifluorophenylacetonitrile is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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