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Pharmacopeial Impurities (EP / USP / BP)

Clobetasol Propionate EP Impurity G

Reference StandardAvailable on request

Buy Clobetasol Propionate EP Impurity G (CAS 25122-41-2) from Zemixal: C22H28ClFO4, COA and SDS with every lot, worldwide shipping.

Pack sizes
Clobetasol Propionate EP Impurity G chemical structure
CAS number25122-41-2
FormulaC22H28ClFO4
Molar mass410.9 g/mol
Physical formSolid
HS code38229090
InChIKeyFCSHDIVRCWTZOX-DVTGEIKXSA-N
IUPAC name(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

About Clobetasol Propionate EP Impurity G

Zemixal lists Clobetasol Propionate EP Impurity G for laboratories that identify, quantify or control Betamethasone and its related substances. Key data (Reference Standard): CAS 25122-41-2, formula C22H28ClFO4 and molar mass 410.9 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Handling and storage

It carries the GHS signal word Danger (H360, H373 and H413), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Betamethasone

See every impurity, metabolite and related compound we list for this API.

Betamethasone standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Clobetasol Propionate EP Impurity G
Product nameClobetasol Propionate EP Impurity G
Catalogue numberZX-019758
CAS number25122-41-2
IUPAC name(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formulaC22H28ClFO4
Molar mass410.9 g/mol
Exact mass410.166
GradeReference Standard
Physical formSolid
XLogP32.5
H-bond donors / acceptors2 / 5
Topological polar surface area74.6 Ų
HS code38229090
InChIKeyFCSHDIVRCWTZOX-DVTGEIKXSA-N
SMILESC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)O)C)O)F)C
PubChem CID5311051
SynonymsClobetasol, Betamethasone EP Impurity B, Betamethasone - Impurity B, Clobetasol Propionate - Impurity G, Clobecort Amex, 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione, (11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, (11, _,16, _)-21-Chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11, A,16, A)-

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H360May damage fertility or the unborn child
  • H373May causes damage to organs through prolonged or repeated exposure
  • H413May cause long lasting harmful effects to aquatic life

Precautionary statements P203, P260, P273, P280, P318, P319, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Clobetasol Propionate EP Impurity G
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Clobetasol Propionate EP Impurity G

Which CAS number identifies Clobetasol Propionate EP Impurity G?
Clobetasol Propionate EP Impurity G is registered under CAS 25122-41-2. You may also see it listed as Clobetasol, Betamethasone EP Impurity B, Betamethasone - Impurity B. Our catalogue number for this item is ZX-019758.
What are the formula and molar mass of Clobetasol Propionate EP Impurity G?
For Clobetasol Propionate EP Impurity G, its formula is C22H28ClFO4 and its molar mass is 410.9 g/mol. The systematic (IUPAC) name is (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one. InChIKey FCSHDIVRCWTZOX-DVTGEIKXSA-N lets you match it in any structure database.
How is Clobetasol Propionate EP Impurity G used in pharmaceutical QC?
Clobetasol Propionate EP Impurity G is a characterised reference material linked to Betamethasone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Clobetasol Propionate EP Impurity G?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Clobetasol Propionate EP Impurity G?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Clobetasol Propionate EP Impurity G to my country?
Yes. Because Clobetasol Propionate EP Impurity G is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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