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3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione

Reference StandardAvailable on request

3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione (CAS 26581-81-7) supplier Zemixal. Request a quote with price, lead time and documents.

Pack sizes
3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione chemical structure
CAS number26581-81-7
FormulaC13H12N2O3
Molar mass244.25 g/mol
Physical formSolid
HS code38229090
InChIKeyWENKGSGGXGQHSH-UHFFFAOYSA-N
IUPAC name3-(3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione

About 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione

3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione belongs to the Thalidomide reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 26581-81-7, formula C13H12N2O3 and molar mass 244.25 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Hazard communication follows GHS (Warning: H302, H315, H319 and H335). Our SDS lists exposure controls and first-aid measures.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Thalidomide

See every impurity, metabolite and related compound we list for this API.

Thalidomide standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Product name3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Catalogue numberZX-027213
CAS number26581-81-7
IUPAC name3-(3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
Molecular formulaC13H12N2O3
Molar mass244.25 g/mol
Exact mass244.0848
GradeReference Standard
Physical formSolid
XLogP30.2
H-bond donors / acceptors1 / 3
Topological polar surface area66.5 Ų
HS code38229090
InChIKeyWENKGSGGXGQHSH-UHFFFAOYSA-N
SMILESC1CC(=O)NC(=O)C1N2CC3=CC=CC=C3C2=O
PubChem CID91585
Synonyms3-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione, 2-(2,6-dioxopiperidin-3-yl)phthalimidine, 2-(1-Oxo-2-isoindolinyl)glutarimide, Glutarimide, 2-(1-oxo-2-isoindolinyl)-, 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-dioxopiperidine, 2-(2,6-dioxopiperidine-3-yl)phthalimidine, Phthalimidinoglutarimide, 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione, 2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, EM-12, em12

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione

Which CAS number identifies 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is registered under CAS 26581-81-7. You may also see it listed as 3-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione, 2-(2,6-dioxopiperidin-3-yl)phthalimidine, 2-(1-Oxo-2-isoindolinyl)glutarimide. Our catalogue number for this item is ZX-027213.
What are the formula and molar mass of 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
For 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione, its formula is C13H12N2O3 and its molar mass is 244.25 g/mol. The systematic (IUPAC) name is 3-(3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione. InChIKey WENKGSGGXGQHSH-UHFFFAOYSA-N lets you match it in any structure database.
How is 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione used in pharmaceutical QC?
3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is a characterised reference material linked to Thalidomide. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione to my country?
Yes. Because 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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