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API Reference Standards

Sorafenib

Reference StandardAvailable on request

Buy Sorafenib (CAS 284461-73-0) from Zemixal. Request a quote with price, lead time and documents. Catalogue no. ZX-006825.

Pack sizes
Sorafenib chemical structure
CAS number284461-73-0
FormulaC21H16ClF3N4O3
Molar mass464.8 g/mol
Physical formSolid
HS code38229090
InChIKeyMLDQJTXFUGDVEO-UHFFFAOYSA-N
IUPAC name4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide

About Sorafenib

Sorafenib belongs to the Sorafenib reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 284461-73-0, formula C21H16ClF3N4O3 and molar mass 464.8 g/mol. It is handled as a solid.

Use cases we see most often

  • Identification & assay
  • Method development & validation
  • QC reference material

Handling and storage

Hazard communication follows GHS (Danger: H351, H360, H361 and H362). Our SDS lists exposure controls and first-aid measures.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. You receive a certificate of analysis with characterisation data with each order. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Sorafenib

See every impurity, metabolite and related compound we list for this API.

Sorafenib standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Sorafenib
Product nameSorafenib
Catalogue numberZX-006825
CAS number284461-73-0
Other CAS numbers475207-59-1
IUPAC name4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
Molecular formulaC21H16ClF3N4O3
Molar mass464.8 g/mol
Exact mass464.0863
GradeReference Standard
Physical formSolid
XLogP34.1
H-bond donors / acceptors3 / 7
Topological polar surface area92.4 Ų
HS code38229090
InChIKeyMLDQJTXFUGDVEO-UHFFFAOYSA-N
SMILESCNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
PubChem CID216239
Synonyms4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide, sorafenib tosilate hydrate, Sorafenib free base, C21H16ClF3N4O3, Sorafenib (Nexavar), 284461-73-0 (free base), 1uwh, 3gcs, 3heg, 4asd, Hit compound, 8, Sorafenib (Base)

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Danger

  • H351Suspected of causing cancer
  • H360May damage fertility or the unborn child
  • H361Suspected of damaging fertility or the unborn child
  • H362May cause harm to breast-fed children
  • H372Causes damage to organs through prolonged or repeated exposure
  • H400Very toxic to aquatic life
  • H402Harmful to aquatic life
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements P203, P260, P263, P264, P270, P273, P280, P318, P319, P391, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Sorafenib
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Sorafenib

Which CAS number identifies Sorafenib?
Sorafenib is registered under CAS 284461-73-0. You may also see it listed as 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide, sorafenib tosilate hydrate, Sorafenib free base. Our catalogue number for this item is ZX-006825.
What are the formula and molar mass of Sorafenib?
For Sorafenib, its formula is C21H16ClF3N4O3 and its molar mass is 464.8 g/mol. The systematic (IUPAC) name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide. InChIKey MLDQJTXFUGDVEO-UHFFFAOYSA-N lets you match it in any structure database.
How is Sorafenib used in pharmaceutical QC?
Sorafenib is a characterised reference material linked to Sorafenib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Sorafenib?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Sorafenib?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Sorafenib to my country?
Yes. Because Sorafenib is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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