Naloxone Hydrochloride

Name: Naloxone Hydrochloride
Brand: Zemixal
SKU: ZX-006668

Reference StandardIn stock

Naloxone Hydrochloride (CAS 357-08-4) supplier Zemixal: C19H22ClNO4, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-006668.

Pack sizes

Naloxone Hydrochloride chemical structure

CAS number357-08-4

FormulaC₁₉H₂₂ClNO₄

Molar mass363.8 g/mol

Physical formSolid

HS code38229090

InChIKeyRGPDIGOSVORSAK-STHHAXOLSA-N

IUPAC name(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride

About Naloxone Hydrochloride

Naloxone Hydrochloride belongs to the Naloxone reference-standard family in the Zemixal catalogue. For your records (Reference Standard), the material is defined by CAS 357-08-4, formula C19H22ClNO4 and molar mass 363.8 g/mol. It is handled as a solid.

Use cases we see most often

Identification & assay
Method development & validation
QC reference material

Handling and storage

It carries the GHS signal word Danger (H302, H315, H318 and H319), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg, 100 mg and 250 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Naloxone

See every impurity, metabolite and related compound we list for this API.

Naloxone standards

Typical uses

Identification & assay
Method development & validation
QC reference material

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Naloxone Hydrochloride
Product name	Naloxone Hydrochloride
Catalogue number	ZX-006668
CAS number	357-08-4
Other CAS numbers	465-65-6, 51481-60-8
IUPAC name	(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
Molecular formula	C₁₉H₂₂ClNO₄
Molar mass	363.8 g/mol
Exact mass	363.1237
Grade	Reference Standard
Physical form	Solid
H-bond donors / acceptors	3 / 5
Topological polar surface area	70 Å²
HS code	38229090
InChIKey	RGPDIGOSVORSAK-STHHAXOLSA-N
SMILES	C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl
PubChem CID	5464092
Synonyms	(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one Hydrochloride, (-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride, N-Allyldihydro-14-hydroxynormorphinone hydrochloride, (-)-Naloxone hydrochloride, Naloxone HCl, NIH 7890, Anhydrous naloxone hydrochloride, Naloxone hydrochloride anhydrous, Naloxoni hydrochloridum anhydrous, Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5alpha)-, Narcan neonatal, Nalxone Hydrochloride

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Corrosive

Irritant or harmful

Signal word Danger

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation

Precautionary statements P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P305 + P354 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Naloxone Hydrochloride
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request
250 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Naloxone Hydrochloride

Which CAS number identifies Naloxone Hydrochloride?

Naloxone Hydrochloride is registered under CAS 357-08-4. You may also see it listed as (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one Hydrochloride, (-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride, N-Allyldihydro-14-hydroxynormorphinone hydrochloride. Our catalogue number for this item is ZX-006668.

What are the formula and molar mass of Naloxone Hydrochloride?

For Naloxone Hydrochloride, its formula is C19H22ClNO4 and its molar mass is 363.8 g/mol. InChIKey RGPDIGOSVORSAK-STHHAXOLSA-N lets you match it in any structure database.

How is Naloxone Hydrochloride used in pharmaceutical QC?

Naloxone Hydrochloride is a characterised reference material linked to Naloxone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Naloxone Hydrochloride?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Naloxone Hydrochloride?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Naloxone Hydrochloride to my country?

Yes. Because Naloxone Hydrochloride is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Naloxone standards

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