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Nitrosamine Impurities

N-Nitroso-D-proline

Reference StandardAvailable on request

Order N-Nitroso-D-proline (CAS 42022-03-7) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery. Part of our Nitrosamine Impurities range.

Pack sizes
N-Nitroso-D-proline chemical structure
CAS number42022-03-7
FormulaC5H8N2O3
Molar mass144.13 g/mol
Physical formSolid
HS code38229090
InChIKeyWLKPHJWEIIAIFW-SCSAIBSYSA-N
IUPAC name(2R)-1-nitrosopyrrolidine-2-carboxylic acid

About N-Nitroso-D-proline

Analytical teams working on Proline use N-Nitroso-D-proline as a qualified comparison standard. Identity at a glance (Reference Standard): CAS 42022-03-7, formula C5H8N2O3 and molar mass 144.13 g/mol. It is handled as a solid.

Typical applications

  • Nitrosamine risk assessment
  • Trace LC-MS/MS quantitation
  • Method validation (AMV)
  • Regulatory submissions

Safe handling

It carries the GHS signal word Warning (H302, H315, H319 and H335), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Proline

See every impurity, metabolite and related compound we list for this API.

Proline standards

Typical uses

  • Nitrosamine risk assessment
  • Trace LC-MS/MS quantitation
  • Method validation (AMV)
  • Regulatory submissions

Applications

Specifications and identifiers

Specifications of N-Nitroso-D-proline
Product nameN-Nitroso-D-proline
Catalogue numberZX-036387
CAS number42022-03-7
IUPAC name(2R)-1-nitrosopyrrolidine-2-carboxylic acid
Molecular formulaC5H8N2O3
Molar mass144.13 g/mol
Exact mass144.0535
GradeReference Standard
Physical formSolid
XLogP30.3
H-bond donors / acceptors1 / 5
Topological polar surface area70 Ų
HS code38229090
InChIKeyWLKPHJWEIIAIFW-SCSAIBSYSA-N
SMILESC1C[C@@H](N(C1)N=O)C(=O)O
PubChem CID29985925
SynonymsN-Nitroso-D-proline (Mixture of Isomers), (R)-1-Nitrosopyrrolidine-2-carboxylic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Warning

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H341Suspected of causing genetic defects
  • H351Suspected of causing cancer

Precautionary statements P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of N-Nitroso-D-proline
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about N-Nitroso-D-proline

Which CAS number identifies N-Nitroso-D-proline?
N-Nitroso-D-proline is registered under CAS 42022-03-7. You may also see it listed as N-Nitroso-D-proline (Mixture of Isomers), (R)-1-Nitrosopyrrolidine-2-carboxylic acid. Our catalogue number for this item is ZX-036387.
What are the formula and molar mass of N-Nitroso-D-proline?
For N-Nitroso-D-proline, its formula is C5H8N2O3 and its molar mass is 144.13 g/mol. The systematic (IUPAC) name is (2R)-1-nitrosopyrrolidine-2-carboxylic acid. InChIKey WLKPHJWEIIAIFW-SCSAIBSYSA-N lets you match it in any structure database.
How is N-Nitroso-D-proline used in pharmaceutical QC?
N-Nitroso-D-proline is a characterised reference material linked to Proline. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for N-Nitroso-D-proline?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with N-Nitroso-D-proline?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship N-Nitroso-D-proline to my country?
Yes. Because N-Nitroso-D-proline is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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CAS
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Formula
C5H10N2O
MW
114.15 g/mol
ZX-026172

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