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API Reference Standards

Naloxone

Reference StandardIn stock

Buy Naloxone (CAS 465-65-6) from Zemixal: C19H21NO4, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-006667.

Pack sizes
Naloxone chemical structure
CAS number465-65-6
FormulaC19H21NO4
Molar mass327.4 g/mol
Physical formSolid
HS code38229090
InChIKeyUZHSEJADLWPNLE-GRGSLBFTSA-N
IUPAC name(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one

About Naloxone

Naloxone is supplied by Zemixal as a characterised reference material for Naloxone analysis. Key data (Reference Standard): CAS 465-65-6, formula C19H21NO4 and molar mass 327.4 g/mol. It is handled as a solid.

Use cases we see most often

  • Identification & assay
  • Method development & validation
  • QC reference material

Storage and safety notes

It carries the GHS signal word Danger (H302, H315, H318 and H319), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg, 100 mg and 250 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Naloxone

See every impurity, metabolite and related compound we list for this API.

Naloxone standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Naloxone
Product nameNaloxone
Catalogue numberZX-006667
CAS number465-65-6
Other CAS numbers357-08-4, 51481-60-8
IUPAC name(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formulaC19H21NO4
Molar mass327.4 g/mol
Exact mass327.1471
GradeReference Standard
Physical formSolid
XLogP32.1
H-bond donors / acceptors2 / 5
Topological polar surface area70 Ų
HS code38229090
InChIKeyUZHSEJADLWPNLE-GRGSLBFTSA-N
SMILESC=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O
PubChem CID5284596
Synonyms(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one, l-Naloxone, (-)-Naloxone, n-Allylnoroxymorphone, EN 1530 base, Nalossone, N-Allyl-noroxymorphone, DBL Naloxone, 1-N-Allyl-14-hydroxynordihydromorphinone, Naloxone Nasal Spray, 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one, 1-N-Allyl-7,8-dihydro-14-hydroxynormorphinone

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS05 Corrosive
Corrosive
GHS07 Irritant or harmful
Irritant or harmful

Signal word Danger

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Naloxone
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Naloxone

Which CAS number identifies Naloxone?
Naloxone is registered under CAS 465-65-6. You may also see it listed as (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one, l-Naloxone, (-)-Naloxone. Our catalogue number for this item is ZX-006667.
What are the formula and molar mass of Naloxone?
For Naloxone, its formula is C19H21NO4 and its molar mass is 327.4 g/mol. The systematic (IUPAC) name is (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one. InChIKey UZHSEJADLWPNLE-GRGSLBFTSA-N lets you match it in any structure database.
How is Naloxone used in pharmaceutical QC?
Naloxone is a characterised reference material linked to Naloxone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Naloxone?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Naloxone?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Naloxone to my country?
Yes. Because Naloxone is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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