Shipping to 128 countriesCOA and SDS with every lotQuotes within one business day
contact@zemixal.com
Bulk CASAccount
API Impurities

Tofacitinib Impurity E

Reference StandardIn stock

Buy Tofacitinib Impurity E (CAS 477600-70-7) from Zemixal. Request a quote with price, lead time and documents. Catalogue no. ZX-005445.

Pack sizes
Tofacitinib Impurity E chemical structure
CAS number477600-70-7
FormulaC14H22N2
Molar mass218.34 g/mol
Physical formSolid
HS code38229090
InChIKeyNVKDDQBZODSEIN-OCCSQVGLSA-N
IUPAC name(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine

About Tofacitinib Impurity E

Tofacitinib Impurity E belongs to the Tofacitinib reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 477600-70-7, formula C14H22N2 and molar mass 218.34 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

Hazard communication follows GHS (Danger: H302, H315, H318 and H335). Our SDS lists exposure controls and first-aid measures.

Available as 10 mg, 25 mg, 50 mg, 100 mg and 250 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Tofacitinib

See every impurity, metabolite and related compound we list for this API.

Tofacitinib standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of Tofacitinib Impurity E
Product nameTofacitinib Impurity E
Catalogue numberZX-005445
CAS number477600-70-7
Other CAS numbers1062580-52-2
IUPAC name(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine
Molecular formulaC14H22N2
Molar mass218.34 g/mol
Exact mass218.1783
GradeReference Standard
Physical formSolid
XLogP32.3
H-bond donors / acceptors1 / 2
Topological polar surface area15.3 Ų
HS code38229090
InChIKeyNVKDDQBZODSEIN-OCCSQVGLSA-N
SMILESC[C@@H]1CCN(C[C@@H]1NC)CC2=CC=CC=C2
PubChem CID44630604
Synonyms(3R,4R)-1-Benzyl-N-methyl-4-methylpiperidin-3-amine, (3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine, cis-1-Benzyl-N,4-dimethylpiperidin-3-amine, (3R,4R)-N,4-Dimethyl-1-benzyl-3-piperidinamine, (3R,4R)-1-benzyl-N,4-dimethyl-piperidin-3-amine, rel-((3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine), Tofacitinib Related Impurity 7, CS-B0451, (3R,4R)-1-benzyl-N,4-dimethyl-3-piperidinamine, 1-Benzyl-N,4-dimethylpiperidin-3-amine, (3R,4R)-, (3R,4R)-(1-Benzyl-4-methylpiperidin-3-yl)-methylamine, (3R,4R)-1-Benzyl-3-(methylamino)-4-methylpiperidine

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS05 Corrosive
Corrosive
GHS07 Irritant or harmful
Irritant or harmful

Signal word Danger

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Tofacitinib Impurity E
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Tofacitinib Impurity E

Which CAS number identifies Tofacitinib Impurity E?
Tofacitinib Impurity E is registered under CAS 477600-70-7. You may also see it listed as (3R,4R)-1-Benzyl-N-methyl-4-methylpiperidin-3-amine, (3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine, cis-1-Benzyl-N,4-dimethylpiperidin-3-amine. Our catalogue number for this item is ZX-005445.
What are the formula and molar mass of Tofacitinib Impurity E?
For Tofacitinib Impurity E, its formula is C14H22N2 and its molar mass is 218.34 g/mol. The systematic (IUPAC) name is (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine. InChIKey NVKDDQBZODSEIN-OCCSQVGLSA-N lets you match it in any structure database.
How is Tofacitinib Impurity E used in pharmaceutical QC?
Tofacitinib Impurity E is a characterised reference material linked to Tofacitinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Tofacitinib Impurity E?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Tofacitinib Impurity E?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Tofacitinib Impurity E to my country?
Yes. Because Tofacitinib Impurity E is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Tofacitinib standards

More in API Impurities

Have a list of compounds to price?

Paste up to 200 CAS numbers into Bulk CAS lookup, or send one enquiry for everything in your quote list. We reply with price, lead time and documents.

Bulk CAS lookup Open quote list
Compare 0 of 4Compare now