Tofacitinib

Name: Tofacitinib
Brand: Zemixal
SKU: ZX-006868

Reference StandardAvailable on request

Tofacitinib (CAS 477600-75-2) supplier Zemixal: C16H20N6O, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-006868.

Pack sizes

CAS number477600-75-2

FormulaC₁₆H₂₀N₆O

Molar mass312.37 g/mol

Physical formSolid

HS code38229090

InChIKeyUJLAWZDWDVHWOW-YPMHNXCESA-N

IUPAC name3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile

About Tofacitinib

Analytical teams working on Tofacitinib use Tofacitinib as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 477600-75-2, formula C16H20N6O and molar mass 312.37 g/mol. It is handled as a solid.

Typical applications

Identification & assay
Method development & validation
QC reference material

Handling and storage

It carries the GHS signal word Danger (H301, H302, H311 and H315), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Tofacitinib

See every impurity, metabolite and related compound we list for this API.

Tofacitinib standards

Typical uses

Identification & assay
Method development & validation
QC reference material

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Tofacitinib
Product name	Tofacitinib
Catalogue number	ZX-006868
CAS number	477600-75-2
Other CAS numbers	540737-29-9
IUPAC name	3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
Molecular formula	C₁₆H₂₀N₆O
Molar mass	312.37 g/mol
Exact mass	312.1699
Grade	Reference Standard
Physical form	Solid
XLogP3	1.5
H-bond donors / acceptors	1 / 5
Topological polar surface area	88.9 Å²
HS code	38229090
InChIKey	UJLAWZDWDVHWOW-YPMHNXCESA-N
SMILES	C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
PubChem CID	9926791
Synonyms	Cp-690 free base, CP-690, JAK inhibitors: tofacitinib, Tofacitinib (CP-690550,Tasocitinib), 4oti, rac-Tofacitinib, Tofacitinib (CP-690550), racemic-tofacitinib, racemic-Tasocitinib, Tofacitinib (USAN), Tofacitinib Base, 3eyg

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Acute toxicity

Irritant or harmful

Health hazard

Signal word Danger

H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Tofacitinib
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Tofacitinib

Which CAS number identifies Tofacitinib?

Tofacitinib is registered under CAS 477600-75-2. You may also see it listed as Cp-690 free base, CP-690, JAK inhibitors: tofacitinib. Our catalogue number for this item is ZX-006868.

What are the formula and molar mass of Tofacitinib?

For Tofacitinib, its formula is C16H20N6O and its molar mass is 312.37 g/mol. The systematic (IUPAC) name is 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile. InChIKey UJLAWZDWDVHWOW-YPMHNXCESA-N lets you match it in any structure database.

How is Tofacitinib used in pharmaceutical QC?

Tofacitinib is a characterised reference material linked to Tofacitinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Tofacitinib?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Tofacitinib?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Tofacitinib to my country?

Yes. Because Tofacitinib is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Tofacitinib standards

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