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Pharmacopeial Impurities (EP / USP / BP)

Cimetidine EP Impurity A

Reference StandardAvailable on request

Order Cimetidine EP Impurity A (CAS 52378-40-2) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery. Catalogue no. ZX-021215.

Pack sizes
Cimetidine EP Impurity A chemical structure
CAS number52378-40-2
FormulaC10H15N5S2
Molar mass269.4 g/mol
Physical formSolid
HS code38229090
InChIKeyWSUNDBVVUCLXTG-UHFFFAOYSA-N
IUPAC namemethyl N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]carbamimidothioate

About Cimetidine EP Impurity A

Zemixal lists Cimetidine EP Impurity A for laboratories that identify, quantify or control Cimetidine and its related substances. For your records (Reference Standard), the material is defined by CAS 52378-40-2, formula C10H15N5S2 and molar mass 269.4 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Safe handling

Hazard communication follows GHS (Danger: H302+H312+H332, H302, H312 and H317). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Cimetidine

See every impurity, metabolite and related compound we list for this API.

Cimetidine standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Cimetidine EP Impurity A
Product nameCimetidine EP Impurity A
Catalogue numberZX-021215
CAS number52378-40-2
IUPAC namemethyl N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]carbamimidothioate
Molecular formulaC10H15N5S2
Molar mass269.4 g/mol
Exact mass269.0769
GradeReference Standard
Physical formSolid
XLogP31.4
H-bond donors / acceptors2 / 5
Topological polar surface area127 Ų
HS code38229090
InChIKeyWSUNDBVVUCLXTG-UHFFFAOYSA-N
SMILESCC1=C(N=CN1)CSCCN=C(NC#N)SC
PubChem CID103630
SynonymsCimetidine Hydrochloride - Impurity A, 1-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea, 1-cyano-2-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]isothiourea, N-Cyano-N'-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea, N-Cyano-N'-2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl-S-methylisothiourea, (E)-methyl N'-cyano-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)carbamimidothioate, methyl N'-cyano-N-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)carbamimidothioate, Methyl N-cyano-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]carbamimidothioate, 3-Cyano-2-methyl-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulphanyl]ethyl]isothiourea, N-cyano-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]-S-methyl isothiourea, N-cyano-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]-S-methylisothiourea, N-cyano-N'-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]-S-methylisothiourea

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H317May cause an allergic skin reaction
  • H332Harmful if inhaled
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Cimetidine EP Impurity A
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Cimetidine EP Impurity A

Which CAS number identifies Cimetidine EP Impurity A?
Cimetidine EP Impurity A is registered under CAS 52378-40-2. You may also see it listed as Cimetidine Hydrochloride - Impurity A, 1-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea, 1-cyano-2-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]isothiourea. Our catalogue number for this item is ZX-021215.
What are the formula and molar mass of Cimetidine EP Impurity A?
For Cimetidine EP Impurity A, its formula is C10H15N5S2 and its molar mass is 269.4 g/mol. The systematic (IUPAC) name is methyl N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]carbamimidothioate. InChIKey WSUNDBVVUCLXTG-UHFFFAOYSA-N lets you match it in any structure database.
How is Cimetidine EP Impurity A used in pharmaceutical QC?
Cimetidine EP Impurity A is a characterised reference material linked to Cimetidine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Cimetidine EP Impurity A?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Cimetidine EP Impurity A?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Cimetidine EP Impurity A to my country?
Yes. Because Cimetidine EP Impurity A is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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